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FACS assay shows that Biotinylated Human 4-1BB, Fc,Avitag (41B-H82F8) can bind to HEK293/Human 4-1BB Ligand / TNFSF9 Stable Cell Line (CHEK-ATP039). HEK293/Human 4-1BB Ligand / TNFSF9 Stable Cell was red line, Negative control HEK293 cells was grey line (QC tested).
GMP Human 4-1BB Ligand Protein, Fc Tag (Cat. No. GMP-41LH26) induce IL‐8 secretion in HT1080 human CD137 cell line. The specific activity of GMP Human 4-1BB Ligand Protein, Fc Tag is>1.00 x 10^5 U/mg (QC tested).
Biotinylated Human 4-1BB Ligand (71-254), Fc,Avitag, premium grade (Cat. No. 41L-H82Fa) captured on Protein A Chip can bind Human 4-1BB, His Tag (Cat. No. 41B-H52Hc) with an affinity constant of 342 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
RTX-224 | RTX-224 | Phase 2 Clinical | Rubius Therapeutics Inc | Skin Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Carcinoma, Non-Small-Cell Lung | Details |
RP-3 | RP-3 | Phase 2 Clinical | Replimune Inc | Solid tumours; Liver Neoplasms; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Hepatocellular | Details |
RTX-224 | RTX-224 | Phase 2 Clinical | Rubius Therapeutics Inc | Skin Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Carcinoma, Non-Small-Cell Lung | Details |
RP-3 | RP-3 | Phase 2 Clinical | Replimune Inc | Solid tumours; Liver Neoplasms; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Hepatocellular | Details |
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