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Cat . Non | Espèces | Description du produit | Structure | Pureté | Caractéristique |
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CHEK-ATP192 | Human | HEK293/Human TrkA Stable Cell Line | |||
TRA-H5253 | Human | Human TrkA / NTRK1 (192-402) Protein, Mouse IgG2a Fc Tag |
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TRA-H5259 | Human | Human TrkA / NTRK1 (33-417) Protein, Mouse IgG2a Fc Tag |
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Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Entrectinib | NMS-E628; RXDX-101; RG-6268 | Approved | Nerviano Medical Sciences Srl | Rozlytrek, 罗圣全 | Japan | Carcinoma, Non-Small-Cell Lung | Chugai Pharmaceutical Co Ltd | 2019-06-18 | Cholangiocarcinoma; Melanoma; Thyroid Cancer, Papillary; Carcinoma, Non-Small-Cell Lung; Glioma; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Lymphoproliferative Disorders; Colorectal Neoplasms; Hepatic Insufficiency; Breast Neoplasms; Brain Neoplasms; Solid tumours; Sarcoma; Neuroendocrine Tumors; Central Nervous System Neoplasms; Pancreatic Neoplasms; Salivary Gland Neoplasms; Neoplasms; Carcinoma, Renal Cell; Hematologic Neoplasms; Skin Melanoma; Ovarian Neoplasms; Head and Neck Neoplasms | Details |
Regorafenib | DAST; BAY-73-4506 | Approved | Bayer AG | Stivarga, Resihance | United States | Colorectal Neoplasms | Bayer Healthcare Pharmaceuticals Inc | 2012-09-27 | Fallopian Tube Neoplasms; Osteosarcoma; Sarcoma, Ewing; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Peritoneal Neoplasms; Bone Neoplasms; Bile Duct Neoplasms; Thymoma; Thyroid Neoplasms; Leukemia, Myeloid, Acute; Gastrinoma; Lung Neoplasms; Esophageal adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Melanoma; Gastrointestinal Neoplasms; Somatostatinoma; Adenocarcinoma; Neoplasm Metastasis; Meningioma; Neoplasms; Solid tumours; Ovarian Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Hemangiosarcoma; Carcinoid Tumor; Insulinoma; Carcinoma, Islet Cell; Stomach Neoplasms; Esophageal Neoplasms; Liver Neoplasms; Carcinoma, Transitional Cell; Colonic Neoplasms; Pancreatic Neoplasms; Glioblastoma; Carcinoma, Ovarian Epithelial; Adenoma; Glucagonoma; Carcinoma, Adenoid Cystic; Sarcoma | Details |
Larotrectinib sulfate | LOXO-101; ARRY-470; BAY-2757556 | Approved | Array Biopharma | Vitrakvi, 维泰凯 | United States | Solid tumours | Bayer Healthcare | 2018-11-26 | Glioma; Central Nervous System Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Histiocytosis, Langerhans-Cell; Cholangiocarcinoma; Osteosarcoma; Sarcoma, Ewing; Neuroblastoma; Sarcoma; Histiocytic Sarcoma; Colorectal Neoplasms; Neoplasms, Neuroepithelial; Urinary Bladder Neoplasms; Thyroid Neoplasms; Carcinoma, Squamous Cell; Lymphoma, Non-Hodgkin; Lymphoma; Uterine Neoplasms; Endometrial Neoplasms; Lung Neoplasms; Uterine Cervical Neoplasms; Neoplasms, Germ Cell and Embryonal; Melanoma; Neuroectodermal Tumors, Primitive, Peripheral; Xanthogranuloma, Juvenile; Squamous Cell Carcinoma of Head and Neck; Solid tumours; Ependymoma; Medulloblastoma; Liver Neoplasms; Fibrosarcoma; Leukemia; Rhabdomyosarcoma; Hematologic Neoplasms; Head and Neck Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Carcinoma, Renal Cell; Ovarian Neoplasms; Hepatoblastoma; Rhabdoid Tumor; Rectal Neoplasms; Neoplasms; Carcinoma, Transitional Cell; Carcinoma, Ovarian Epithelial; Pancreatic Neoplasms; Wilms Tumor; Colonic Neoplasms; Ski | Details |
Entrectinib | NMS-E628; RXDX-101; RG-6268 | Approved | Nerviano Medical Sciences Srl | Rozlytrek, 罗圣全 | Japan | Carcinoma, Non-Small-Cell Lung | Chugai Pharmaceutical Co Ltd | 2019-06-18 | Cholangiocarcinoma; Melanoma; Thyroid Cancer, Papillary; Carcinoma, Non-Small-Cell Lung; Glioma; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Lymphoproliferative Disorders; Colorectal Neoplasms; Hepatic Insufficiency; Breast Neoplasms; Brain Neoplasms; Solid tumours; Sarcoma; Neuroendocrine Tumors; Central Nervous System Neoplasms; Pancreatic Neoplasms; Salivary Gland Neoplasms; Neoplasms; Carcinoma, Renal Cell; Hematologic Neoplasms; Skin Melanoma; Ovarian Neoplasms; Head and Neck Neoplasms | Details |
Regorafenib | DAST; BAY-73-4506 | Approved | Bayer AG | Stivarga, Resihance | United States | Colorectal Neoplasms | Bayer Healthcare Pharmaceuticals Inc | 2012-09-27 | Fallopian Tube Neoplasms; Osteosarcoma; Sarcoma, Ewing; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Peritoneal Neoplasms; Bone Neoplasms; Bile Duct Neoplasms; Thymoma; Thyroid Neoplasms; Leukemia, Myeloid, Acute; Gastrinoma; Lung Neoplasms; Esophageal adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Melanoma; Gastrointestinal Neoplasms; Somatostatinoma; Adenocarcinoma; Neoplasm Metastasis; Meningioma; Neoplasms; Solid tumours; Ovarian Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Hemangiosarcoma; Carcinoid Tumor; Insulinoma; Carcinoma, Islet Cell; Stomach Neoplasms; Esophageal Neoplasms; Liver Neoplasms; Carcinoma, Transitional Cell; Colonic Neoplasms; Pancreatic Neoplasms; Glioblastoma; Carcinoma, Ovarian Epithelial; Adenoma; Glucagonoma; Carcinoma, Adenoid Cystic; Sarcoma | Details |
Larotrectinib sulfate | LOXO-101; ARRY-470; BAY-2757556 | Approved | Array Biopharma | Vitrakvi, 维泰凯 | United States | Solid tumours | Bayer Healthcare | 2018-11-26 | Glioma; Central Nervous System Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Histiocytosis, Langerhans-Cell; Cholangiocarcinoma; Osteosarcoma; Sarcoma, Ewing; Neuroblastoma; Sarcoma; Histiocytic Sarcoma; Colorectal Neoplasms; Neoplasms, Neuroepithelial; Urinary Bladder Neoplasms; Thyroid Neoplasms; Carcinoma, Squamous Cell; Lymphoma, Non-Hodgkin; Lymphoma; Uterine Neoplasms; Endometrial Neoplasms; Lung Neoplasms; Uterine Cervical Neoplasms; Neoplasms, Germ Cell and Embryonal; Melanoma; Neuroectodermal Tumors, Primitive, Peripheral; Xanthogranuloma, Juvenile; Squamous Cell Carcinoma of Head and Neck; Solid tumours; Ependymoma; Medulloblastoma; Liver Neoplasms; Fibrosarcoma; Leukemia; Rhabdomyosarcoma; Hematologic Neoplasms; Head and Neck Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Carcinoma, Renal Cell; Ovarian Neoplasms; Hepatoblastoma; Rhabdoid Tumor; Rectal Neoplasms; Neoplasms; Carcinoma, Transitional Cell; Carcinoma, Ovarian Epithelial; Pancreatic Neoplasms; Wilms Tumor; Colonic Neoplasms; Ski | Details |
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Tavilermide | MIM-D3; NMG938VJ6T (UNII code) | Phase 3 Clinical | Mimetogen Pharmaceuticals | Keratoconjunctivitis Sicca; Dry Eye Syndromes | Details |
Lestaurtinib | SPM-924; A-154475.0; KT-5555; SP-924; CEP-701 | Phase 3 Clinical | Kyowa Hakko Kirin Co Ltd | Leukemia, Myeloid; Bone Marrow Neoplasms; Leukemia; Polycythemia Vera; Prostatic Neoplasms; Psoriasis; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neuroblastoma; Primary Myelofibrosis; Leukemia, Myeloid, Acute; Thrombocythemia, Essential | Details |
SNA-125 | CT-340; SNA-125 | Phase 2 Clinical | Sienna Biopharmaceuticals Inc, Creabilis Sa | Pruritus; Psoriasis; Dermatitis, Atopic | Details |
Merestinib | 5OGS5K699E; LY-2801653 | Phase 2 Clinical | Eli Lilly And Company | Biliary Tract Neoplasms; Skin Melanoma; Bone metastases; Solid tumours; Neoplasms; Pancreatic Neoplasms; Microsatellite instability-high cancer; Lymphoma, Mantle-Cell; Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Gallbladder Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung | Details |
Milciclib maleate | PHA-848125; TZLS-201; PHA-848125C; PHA-125; PHA-848125AC | Phase 2 Clinical | Tiziana Life Sciences Plc, Nerviano Medical Sciences Srl | Solid tumours; Thymoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung | Details |
VC-004 | VC004; VC-004; VC 004 | Phase 2 Clinical | Jiangsu Vcare Pharmatech Co Ltd | Solid tumours; Pruritus; Cancer Pain; Dermatitis; Neoplasm Metastasis | Details |
XZP-5955 | XZP-5955 | Phase 2 Clinical | Xuanzhu (Shijiazhuang) Biotechnology Co Ltd | Solid tumours; Carcinoma, Non-Small-Cell Lung | Details |
BEN-2293 | BEN-00002293; BEN-2293 | Phase 2 Clinical | Benevolentai Bio Ltd | Dermatitis, Atopic | Details |
TQB-3558 | TQB-3558; CT-3417 | Phase 1 Clinical | Beijing Centaurus Biopharma Co Ltd, Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd | Solid tumours | Details |
ACD-856 | ACD-856 | Phase 1 Clinical | Alzecure Pharma Ab | Alzheimer Disease; Cognition Disorders | Details |
HG-030 | HG-030 | Phase 1 Clinical | Hitgen Inc | Solid tumours | Details |
AK-1830 | AK-1830 | Phase 1 Clinical | Array Biopharma | Inflammation | Details |
BR-01T | BR01T; BR-01T | Phase 1 Clinical | Xiyuan Anjian Pharmaceutical (Shanghai) Co Ltd | Low Back Pain | Details |
ND-003 (NewDEL Biotech) | ND-003; ND003 | Phase 1 Clinical | Shenzhen NewDEL Biotech Co Ltd | Solid tumours; Neoplasms; Idiopathic Pulmonary Fibrosis; Renal fibrosis; Pulmonary Fibrosis; Renal Insufficiency, Chronic; Dermatitis, Atopic | Details |
JND-5932 | JND-5932; JND5932 | Phase 1 Clinical | Jinan University | Neoplasms | Details |
PBI-200 | PBI-200 | Phase 1 Clinical | Pyramid Biosciences | Solid tumours; Desmoplastic Small Round Cell Tumor; Brain Neoplasms | Details |
TQB-3811 | TQB-3811; CT-3872 | Phase 1 Clinical | Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd, Beijing Centaurus Biopharma Co Ltd | Solid tumours | Details |
FCN-098 | FCN-098; FCN098 | Phase 1 Clinical | Fochon Pharmaceuticals Ltd, Fochon Pharmaceuticals Ltd | Solid tumours; Neoplasms | Details |
E-2511 | E2511; E-2511 | Phase 1 Clinical | Eisai Inc | Details | |
Beta-Nerve Growth Factor, Human (Aalborg University) | Phase 1 Clinical | Aalborg University Shakespeare Company | Pain; Hyperalgesia | Details | |
Recombinant human nerve growth factor (Beijing Tongren Hospital) | Phase 1 Clinical | Beijing Tongren Hospital, Cmu | Optic Nerve Injuries | Details | |
VMD-928 | VMD-928 | Phase 1 Clinical | Vm Oncology Llc | Head and Neck Neoplasms; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Mesothelioma; Carcinoma, Adenoid Cystic; Sarcoma; Breast Neoplasms; Thymoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms | Details |
Tavilermide | MIM-D3; NMG938VJ6T (UNII code) | Phase 3 Clinical | Mimetogen Pharmaceuticals | Keratoconjunctivitis Sicca; Dry Eye Syndromes | Details |
Lestaurtinib | SPM-924; A-154475.0; KT-5555; SP-924; CEP-701 | Phase 3 Clinical | Kyowa Hakko Kirin Co Ltd | Leukemia, Myeloid; Bone Marrow Neoplasms; Leukemia; Polycythemia Vera; Prostatic Neoplasms; Psoriasis; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neuroblastoma; Primary Myelofibrosis; Leukemia, Myeloid, Acute; Thrombocythemia, Essential | Details |
SNA-125 | CT-340; SNA-125 | Phase 2 Clinical | Sienna Biopharmaceuticals Inc, Creabilis Sa | Pruritus; Psoriasis; Dermatitis, Atopic | Details |
Merestinib | 5OGS5K699E; LY-2801653 | Phase 2 Clinical | Eli Lilly And Company | Biliary Tract Neoplasms; Skin Melanoma; Bone metastases; Solid tumours; Neoplasms; Pancreatic Neoplasms; Microsatellite instability-high cancer; Lymphoma, Mantle-Cell; Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Gallbladder Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung | Details |
Milciclib maleate | PHA-848125; TZLS-201; PHA-848125C; PHA-125; PHA-848125AC | Phase 2 Clinical | Tiziana Life Sciences Plc, Nerviano Medical Sciences Srl | Solid tumours; Thymoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung | Details |
VC-004 | VC004; VC-004; VC 004 | Phase 2 Clinical | Jiangsu Vcare Pharmatech Co Ltd | Solid tumours; Pruritus; Cancer Pain; Dermatitis; Neoplasm Metastasis | Details |
XZP-5955 | XZP-5955 | Phase 2 Clinical | Xuanzhu (Shijiazhuang) Biotechnology Co Ltd | Solid tumours; Carcinoma, Non-Small-Cell Lung | Details |
BEN-2293 | BEN-00002293; BEN-2293 | Phase 2 Clinical | Benevolentai Bio Ltd | Dermatitis, Atopic | Details |
TQB-3558 | TQB-3558; CT-3417 | Phase 1 Clinical | Beijing Centaurus Biopharma Co Ltd, Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd | Solid tumours | Details |
ACD-856 | ACD-856 | Phase 1 Clinical | Alzecure Pharma Ab | Alzheimer Disease; Cognition Disorders | Details |
HG-030 | HG-030 | Phase 1 Clinical | Hitgen Inc | Solid tumours | Details |
AK-1830 | AK-1830 | Phase 1 Clinical | Array Biopharma | Inflammation | Details |
BR-01T | BR01T; BR-01T | Phase 1 Clinical | Xiyuan Anjian Pharmaceutical (Shanghai) Co Ltd | Low Back Pain | Details |
ND-003 (NewDEL Biotech) | ND-003; ND003 | Phase 1 Clinical | Shenzhen NewDEL Biotech Co Ltd | Solid tumours; Neoplasms; Idiopathic Pulmonary Fibrosis; Renal fibrosis; Pulmonary Fibrosis; Renal Insufficiency, Chronic; Dermatitis, Atopic | Details |
JND-5932 | JND-5932; JND5932 | Phase 1 Clinical | Jinan University | Neoplasms | Details |
PBI-200 | PBI-200 | Phase 1 Clinical | Pyramid Biosciences | Solid tumours; Desmoplastic Small Round Cell Tumor; Brain Neoplasms | Details |
TQB-3811 | TQB-3811; CT-3872 | Phase 1 Clinical | Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd, Beijing Centaurus Biopharma Co Ltd | Solid tumours | Details |
FCN-098 | FCN-098; FCN098 | Phase 1 Clinical | Fochon Pharmaceuticals Ltd, Fochon Pharmaceuticals Ltd | Solid tumours; Neoplasms | Details |
E-2511 | E2511; E-2511 | Phase 1 Clinical | Eisai Inc | Details | |
Beta-Nerve Growth Factor, Human (Aalborg University) | Phase 1 Clinical | Aalborg University Shakespeare Company | Pain; Hyperalgesia | Details | |
Recombinant human nerve growth factor (Beijing Tongren Hospital) | Phase 1 Clinical | Beijing Tongren Hospital, Cmu | Optic Nerve Injuries | Details | |
VMD-928 | VMD-928 | Phase 1 Clinical | Vm Oncology Llc | Head and Neck Neoplasms; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Mesothelioma; Carcinoma, Adenoid Cystic; Sarcoma; Breast Neoplasms; Thymoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms | Details |
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