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Your Position: Accueil > Protein > LILRA2 > LI2-H82E9

Biotinylated Human LILRA2 / CD85h / ILT1 Protein, His,Avitag™

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  • Synonyme
    ILT1,LIR7,CD85H,LIR-7,LILRA2,ILT1CD85H,CD85h,ILT1,ILT-1,ILT1CD85H,CD85h antigen,CD85 antigen-like family member H
  • Source
    Biotinylated Human LILRA2, His,Avitag (LI2-H82E9) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Asn 449 (Accession # Q8N149-1).
    Predicted N-terminus: Gly 24
  • Caractérisation moléculaire
    Online(Gly 24 - Asn 449) Q8N149-1

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 50.7 kDa. The protein migrates as 67-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Biotinylation
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
  • Biotin:Protein Ratio
    Passed as determined by the HABA assay / binding ELISA.
  • Endotoxine
    Less than 1.0 EU per μg by the LAL method.
  • Pureté

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Stockage:

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Biotinylated Human LILRA2, His,Avitag (Cat. No. LI2-H82E9) SDS-PAGE gel

Biotinylated Human LILRA2, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • CONTEXTE
    LILRA2 (Leukocyte immunoglobulin like receptor A2), also known as CD85H and LIR7 (Leukocyte immunoglobulin-like receptor 7). It belongs to the subfamily A class of LIR receptors (LILRAs), which are single-pass type I transmembrane proteins with 2-4 extracellular Ig-like domains, a transmembrane domain (TM), and a short cytoplasmic tail. LILRA2 contains 4 Ig-like C2 type domains in the extracellular region. LILRA2 does not bind class I MHC antigens. LILRA2 is expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. LILRA2 is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(EUR) : €350.00

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