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Your Position: Accueil > Protein > Frizzled-10 > FRD-H52H3

Human Frizzled-10 / FZD10 Protein, His Tag (MALS verified)

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  • Synonyme
    Fz-10,FZD10,hFz10,FzE7,CD350
  • Source
    Human Frizzled-10, His Tag (FRD-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Gly 161 (Accession # Q9ULW2-1).
    Predicted N-terminus: Ile 21
  • Caractérisation moléculaire
    Online(Ile 21 - Gly 161) Q9ULW2-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 18.0 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxine
    Less than 1.0 EU per μg by the LAL method.
  • Pureté

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Stockage:

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human Frizzled-10, His Tag (Cat. No. FRD-H52H3) SDS-PAGE gel

Human Frizzled-10, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

SEC-MALS
Human Frizzled-10, His Tag (Cat. No. ) MALS images

The purity of Human Frizzled-10, His Tag (Cat. No. FRD-H52H3) is more than 90% and the molecular weight of this protein is around 18-25 kDa verified by SEC-MALS.

  • CONTEXTE
    Frizzled-10 (FZD10) is also known as FzE7 or CD350, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD10 contains one FZ (frizzled) domain. FZD10 protein is a cell surface receptor, which is activated by Wnt proteins and involved in the regulation of cellular function. FZD10 interacts with WNT7B and MYOC.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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ETA des produits en stock: 2 jours ouvrables

Price(EUR) : €350.00

Price(EUR) : €2570.00

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  • Latest Research Phase:Discontinued

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