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Your Position: Accueil > Protein > CEACAM-5 > CE5-C52H5

Cynomolgus CEACAM-5 / CD66e Protein, His Tag (MALS verified)

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  • Synonym
    CEACAM-5,CD66e,CEA,Meconium antigen 100
  • Source
    Cynomolgus CEACAM-5, His Tag(CE5-C52H5) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Gly 685 (Accession # XP_005589491.1).
    Predicted N-terminus: Gln 35
  • Molecular Characterization
    CEACAM-5 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 73.6 kDa. The protein migrates as 100-170 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CEACAM-5 SDS-PAGE

Cynomolgus CEACAM-5, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
CEACAM-5 MALS images

The purity of Cynomolgus CEACAM-5, His Tag (Cat. No. CE5-C52H5) is more than 90% and the molecular weight of this protein is around 230-260 kDa verified by SEC-MALS.

  • Background
    Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.
  • Clinical and Translational Updates

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Price(EUR) : €300.00

Price(EUR) : €2200.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:10 Details
  • Latest Research Phase:Phase 3 Clinical

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