0
Il n'y a pas de produit dans le panier !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Accueil > Protein > B7-H4 > B74-M52H9

Mouse B7-H4 Protein, His Tag

Order Now

  • Synonyme
    B7-H4,VTCN1,B7S1,B7h.5
  • Source
    Mouse B7-H4, His Tag (B74-M52H9) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Gly 257 (Accession # Q7TSP5-1).
  • Caractérisation moléculaire
    Online(Leu 25 - Gly 257) Q7TSP5-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 27.6 kDa. The protein migrates as 45-66kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxine
    Less than 1.0 EU per μg by the LAL method.
  • Pureté

    >90% as determined by reduced SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Stockage:

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Mouse B7-H4, His Tag (Cat. No. B74-M52H9) SDS-PAGE gel

Mouse B7-H4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • CONTEXTE
    V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Comments (0)


ETA des produits en stock: 2 jours ouvrables

Price(EUR) : €350.00

Price(EUR) : €2570.00

Promotion & Exhibitions



Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:11 Details
  • Latest Research Phase:Phase 2 Clinical

Datasheet & Documentation

Request for DMF
DMF (Drug Master File)

Related Products

New Product Launch

Questions & Comments

This web search service is supported by Google Inc.

totop

Laisser un message