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Human Amyloid-like protein 2 / APLP2 Protein, His Tag (MALS verified)

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  • Synonym
    Amyloid beta precursor like protein 2,APLP2,APPH,CDEBP,APPL2
  • Source
    Human APLP2, His Tag (AP2-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 692 (Accession # Q06481-1).
    Predicted N-terminus: Gly 32
  • Molecular Characterization
    Online(Gly 32 - Ser 692) Q06481-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 77.9 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human APLP2, His Tag (Cat. No. AP2-H52H9) SDS-PAGE gel

Human APLP2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Human APLP2, His Tag (Cat. No. ) MALS images

The purity of Human APLP2, His Tag (Cat. No. AP2-H52H9) is more than 90% and the molecular weight of this protein is around 80-105 kDa verified by SEC-MALS.

  • Background
    May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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ETA des produits en stock: 2 jours ouvrables

Price(EUR) : €400.00

Price(EUR) : €3110.00

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