Vimseltinib |
DCC-3014 |
Phase 3 Clinical |
Deciphera |
Giant Cell Tumor of Tendon Sheath; Synovitis, Pigmented Villonodular; Neoplasms |
Details
|
Chiauranib |
CS-2164; CS2164 |
Phase 3 Clinical |
Shenzhen Chipscreen Biosciences Co Ltd |
Solid tumours; Ovarian Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Small Cell Lung Carcinoma; Sarcoma; Lymphoma, Non-Hodgkin; Carcinoma, Hepatocellular |
Details
|
Pimicotinib |
ABSK-021 |
Phase 3 Clinical |
ABbisko Therapeutics Co Ltd |
Giant Cell Tumor of Tendon Sheath; Solid tumours; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Neoplasms; Graft vs Host Disease; Sarcoma; Lung Neoplasms; Amyotrophic Lateral Sclerosis |
Details
|
Emactuzumab |
RG-7155; 6FY6EI1X8R; RO-5509554 |
Phase 3 Clinical |
F. Hoffmann-La Roche Ltd |
Solid tumours; Head and Neck Neoplasms; Carcinoma; Neoplasms; Prostatic Neoplasms; Testicular Neoplasms; Lymphoma, Non-Hodgkin; Carcinoma, Squamous Cell |
Details
|
Recombinant human GM-CSF oncolytic herpes simplex virus type 2 (OH2) |
BS-001; BS001; oHSV-2; OH-2; OH2 |
Phase 3 Clinical |
Wuhan Binhui Biotechnology Co Ltd |
Central Nervous System Neoplasms; Melanoma; Lymphoma; Lung Neoplasms; Colorectal Neoplasms; Bile Duct Neoplasms; Breast Neoplasms; Sarcoma; Liver Diseases; Solid tumours; Digestive System Neoplasms; Urinary Bladder Neoplasms; Neoplasms; Pancreatic Neoplasms; Esophageal Neoplasms; Liver Neoplasms; Head and Neck Neoplasms |
Details
|
Tinengotinib |
TT-00420; TT 00420; TT00420 |
Phase 3 Clinical |
TransThera Sciences (Nanjing) Inc |
Biliary Tract Neoplasms; Solid tumours; Kidney Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Triple Negative Breast Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Transitional Cell; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Sarcoma; Thyroid Neoplasms; Gallbladder Neoplasms |
Details
|
LY-3022855 |
IMC-CS4; LY-3022855 |
Phase 2 Clinical |
Eli Lilly And Company |
Solid tumours; Pancreatic Neoplasms; Neoplasms; Neoplasm Metastasis; Melanoma |
Details
|
Simmitinib hydrochloride |
SOMCL-15-290 |
Phase 2 Clinical |
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences |
Solid tumours; Neoplasms; Esophageal Squamous Cell Carcinoma |
Details
|
NMS-03592088 |
NMS-P088; NMS-03592088 |
Phase 2 Clinical |
Nerviano Medical Sciences Srl |
Leukemia, Myelomonocytic, Chronic; Leukemia, Myeloid, Acute |
Details
|
Cabiralizumab |
FPA-008; ONO-4687; BMS-986227 |
Phase 2 Clinical |
Five Prime Therapeutics Inc |
Solid tumours; Head and Neck Neoplasms; Ovarian Neoplasms; Giant Cell Tumor of Tendon Sheath; Lymphoma, T-Cell, Peripheral; Carcinoma, Renal Cell; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Neoplasms; Pancreatic Neoplasms; Arthritis, Rheumatoid; Glioma; Carcinoma, Non-Small-Cell Lung |
Details
|
Derazantinib |
ARQ-087.2HCl; AQ-14741087; ARQ-087; BAL-087 |
Phase 2 Clinical |
Arqule Inc |
Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Carcinoma, Transitional Cell; Cholangiocarcinoma; Urogenital Neoplasms; Carcinoma, Hepatocellular |
Details
|
HH185 |
3D-185; 3-D185; HH-185; 3D185 |
Phase 2 Clinical |
ShangHai HaiHe Biopharma Co Ltd, Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Medicilon Inc |
Solid tumours; Cholangiocarcinoma |
Details
|
C-019199 |
C019199 |
Phase 2 Clinical |
Fujian Haixi Pharmaceuticals Co Ltd |
Solid tumours |
Details
|
Edicotinib |
PRV-6527; JNJ-244; JNJ-40346527-AAC-G-002; JNJ-40346527; JNJ-527 |
Phase 2 Clinical |
Johnson & Johnson |
Arthritis, Rheumatoid; Hodgkin Disease; Prostatic Neoplasms; Alzheimer Disease; Cognitive Dysfunction; Leukemia, Myeloid, Acute; Crohn Disease |
Details
|
Sotuletinib |
BLZ-945 |
Phase 2 Clinical |
Novartis Pharma Ag, Celgene Corp |
Solid tumours; Amyotrophic Lateral Sclerosis |
Details
|
Elzovantinib |
TPX-0022 |
Phase 2 Clinical |
Turning Point Therapeutics Inc |
Solid tumours; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis |
Details
|
[11C]CPPC |
|
Phase 2 Clinical |
Johns Hopkins University |
Post-Acute COVID-19 Syndrome; Amyotrophic Lateral Sclerosis |
Details
|
AMB-05X |
AMB-05X |
Phase 2 Clinical |
Amgen Inc |
Giant Cell Tumor of Tendon Sheath; Synovitis, Pigmented Villonodular; Idiopathic Pulmonary Fibrosis; Testicular Neoplasms |
Details
|
Q-702 |
Q-702 |
Phase 2 Clinical |
Vichem Chemie, Max Planck Institute of Biochemistry, Lead Discovery Center GmbH |
Solid tumours; Liver Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Neoplasm Metastasis; Uterine Cervical Neoplasms |
Details
|
PMI-04 |
|
Phase 1 Clinical |
Precision Molecular Inc |
Nerve Degeneration |
Details
|
APL-102 |
APL-102; CBT-102 |
Phase 1 Clinical |
Apollomics Inc |
Solid tumours |
Details
|
Pamufetinib |
TAS-115 |
Phase 1 Clinical |
Taiho Pharmaceutical Co Ltd, Otsuka Pharmaceutical Co Ltd |
Neoplasms |
Details
|
JDB-383 |
JDB-383 |
Phase 1 Clinical |
Shanghai Jiabao Yaoyin Pharmaceutical Technology Co Ltd |
Giant Cell Tumor of Tendon Sheath |
Details
|
HMPL-653 |
HMPL-653 |
Phase 1 Clinical |
Hutchison Medipharma Ltd |
Giant Cell Tumor of Tendon Sheath; Solid tumours; Testicular Neoplasms |
Details
|
ETH-155036 |
ETH-155036; ETH155036 |
Phase 1 Clinical |
Shengke Pharmaceutical (Jiangsu) Co Ltd |
Myelodysplastic Syndromes; Leukemia, Myeloid, Acute |
Details
|
Caflanone |
FBL-03G |
Phase 1 Clinical |
Flavocure Biotech Inc |
Pancreatic Neoplasms |
Details
|
EI-1071 |
EI-1071; FB-1071 |
Phase 1 Clinical |
Elixiron Immunotherapeutics Inc |
Giant Cell Tumor of Tendon Sheath; Alzheimer Disease; Nervous System Diseases; Amyotrophic Lateral Sclerosis |
Details
|
SYHA-1817 |
SYHA-1817 |
Phase 1 Clinical |
CSPC Pharmaceutical Group Ltd |
Biliary Tract Neoplasms; Stomach Neoplasms; Carcinoma, Squamous Cell |
Details
|
TT-00420/Atezolizumab |
|
Phase 1 Clinical |
TransThera Sciences (Nanjing) Inc |
Gastrointestinal Neoplasms |
Details
|
BC-006 |
BC-006; BC006 |
Phase 1 Clinical |
Dragonboat Biopharmaceutical |
Solid tumours; Giant Cell Tumor of Tendon Sheath |
Details
|
AGX-0073 |
AGX-0073 |
Phase 1 Clinical |
Shanghai Aojian Biological Technology Co Ltd |
Solid tumours |
Details
|
SYHA-1813 |
SYHA1813 |
Phase 1 Clinical |
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Runshi Pharmaceutical Technology Co Ltd |
Giant Cell Tumor of Tendon Sheath; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Gliosarcoma; Colorectal Neoplasms; Brain metastases; Thyroid Neoplasms; Lung Neoplasms; Glioma |
Details
|
Vimseltinib |
DCC-3014 |
Phase 3 Clinical |
Deciphera |
Giant Cell Tumor of Tendon Sheath; Synovitis, Pigmented Villonodular; Neoplasms |
Details
|
Chiauranib |
CS-2164; CS2164 |
Phase 3 Clinical |
Shenzhen Chipscreen Biosciences Co Ltd |
Solid tumours; Ovarian Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Small Cell Lung Carcinoma; Sarcoma; Lymphoma, Non-Hodgkin; Carcinoma, Hepatocellular |
Details
|
Pimicotinib |
ABSK-021 |
Phase 3 Clinical |
ABbisko Therapeutics Co Ltd |
Giant Cell Tumor of Tendon Sheath; Solid tumours; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Neoplasms; Graft vs Host Disease; Sarcoma; Lung Neoplasms; Amyotrophic Lateral Sclerosis |
Details
|
Emactuzumab |
RG-7155; 6FY6EI1X8R; RO-5509554 |
Phase 3 Clinical |
F. Hoffmann-La Roche Ltd |
Solid tumours; Head and Neck Neoplasms; Carcinoma; Neoplasms; Prostatic Neoplasms; Testicular Neoplasms; Lymphoma, Non-Hodgkin; Carcinoma, Squamous Cell |
Details
|
Recombinant human GM-CSF oncolytic herpes simplex virus type 2 (OH2) |
BS-001; BS001; oHSV-2; OH-2; OH2 |
Phase 3 Clinical |
Wuhan Binhui Biotechnology Co Ltd |
Central Nervous System Neoplasms; Melanoma; Lymphoma; Lung Neoplasms; Colorectal Neoplasms; Bile Duct Neoplasms; Breast Neoplasms; Sarcoma; Liver Diseases; Solid tumours; Digestive System Neoplasms; Urinary Bladder Neoplasms; Neoplasms; Pancreatic Neoplasms; Esophageal Neoplasms; Liver Neoplasms; Head and Neck Neoplasms |
Details
|
Tinengotinib |
TT-00420; TT 00420; TT00420 |
Phase 3 Clinical |
TransThera Sciences (Nanjing) Inc |
Biliary Tract Neoplasms; Solid tumours; Kidney Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Triple Negative Breast Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Transitional Cell; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Sarcoma; Thyroid Neoplasms; Gallbladder Neoplasms |
Details
|
LY-3022855 |
IMC-CS4; LY-3022855 |
Phase 2 Clinical |
Eli Lilly And Company |
Solid tumours; Pancreatic Neoplasms; Neoplasms; Neoplasm Metastasis; Melanoma |
Details
|
Simmitinib hydrochloride |
SOMCL-15-290 |
Phase 2 Clinical |
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences |
Solid tumours; Neoplasms; Esophageal Squamous Cell Carcinoma |
Details
|
NMS-03592088 |
NMS-P088; NMS-03592088 |
Phase 2 Clinical |
Nerviano Medical Sciences Srl |
Leukemia, Myelomonocytic, Chronic; Leukemia, Myeloid, Acute |
Details
|
Cabiralizumab |
FPA-008; ONO-4687; BMS-986227 |
Phase 2 Clinical |
Five Prime Therapeutics Inc |
Solid tumours; Head and Neck Neoplasms; Ovarian Neoplasms; Giant Cell Tumor of Tendon Sheath; Lymphoma, T-Cell, Peripheral; Carcinoma, Renal Cell; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Neoplasms; Pancreatic Neoplasms; Arthritis, Rheumatoid; Glioma; Carcinoma, Non-Small-Cell Lung |
Details
|
Derazantinib |
ARQ-087.2HCl; AQ-14741087; ARQ-087; BAL-087 |
Phase 2 Clinical |
Arqule Inc |
Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Carcinoma, Transitional Cell; Cholangiocarcinoma; Urogenital Neoplasms; Carcinoma, Hepatocellular |
Details
|
HH185 |
3D-185; 3-D185; HH-185; 3D185 |
Phase 2 Clinical |
ShangHai HaiHe Biopharma Co Ltd, Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Medicilon Inc |
Solid tumours; Cholangiocarcinoma |
Details
|
C-019199 |
C019199 |
Phase 2 Clinical |
Fujian Haixi Pharmaceuticals Co Ltd |
Solid tumours |
Details
|
Edicotinib |
PRV-6527; JNJ-244; JNJ-40346527-AAC-G-002; JNJ-40346527; JNJ-527 |
Phase 2 Clinical |
Johnson & Johnson |
Arthritis, Rheumatoid; Hodgkin Disease; Prostatic Neoplasms; Alzheimer Disease; Cognitive Dysfunction; Leukemia, Myeloid, Acute; Crohn Disease |
Details
|
Sotuletinib |
BLZ-945 |
Phase 2 Clinical |
Novartis Pharma Ag, Celgene Corp |
Solid tumours; Amyotrophic Lateral Sclerosis |
Details
|
Elzovantinib |
TPX-0022 |
Phase 2 Clinical |
Turning Point Therapeutics Inc |
Solid tumours; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis |
Details
|
[11C]CPPC |
|
Phase 2 Clinical |
Johns Hopkins University |
Post-Acute COVID-19 Syndrome; Amyotrophic Lateral Sclerosis |
Details
|
AMB-05X |
AMB-05X |
Phase 2 Clinical |
Amgen Inc |
Giant Cell Tumor of Tendon Sheath; Synovitis, Pigmented Villonodular; Idiopathic Pulmonary Fibrosis; Testicular Neoplasms |
Details
|
Q-702 |
Q-702 |
Phase 2 Clinical |
Vichem Chemie, Max Planck Institute of Biochemistry, Lead Discovery Center GmbH |
Solid tumours; Liver Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Neoplasm Metastasis; Uterine Cervical Neoplasms |
Details
|
PMI-04 |
|
Phase 1 Clinical |
Precision Molecular Inc |
Nerve Degeneration |
Details
|
APL-102 |
APL-102; CBT-102 |
Phase 1 Clinical |
Apollomics Inc |
Solid tumours |
Details
|
Pamufetinib |
TAS-115 |
Phase 1 Clinical |
Taiho Pharmaceutical Co Ltd, Otsuka Pharmaceutical Co Ltd |
Neoplasms |
Details
|
JDB-383 |
JDB-383 |
Phase 1 Clinical |
Shanghai Jiabao Yaoyin Pharmaceutical Technology Co Ltd |
Giant Cell Tumor of Tendon Sheath |
Details
|
HMPL-653 |
HMPL-653 |
Phase 1 Clinical |
Hutchison Medipharma Ltd |
Giant Cell Tumor of Tendon Sheath; Solid tumours; Testicular Neoplasms |
Details
|
ETH-155036 |
ETH-155036; ETH155036 |
Phase 1 Clinical |
Shengke Pharmaceutical (Jiangsu) Co Ltd |
Myelodysplastic Syndromes; Leukemia, Myeloid, Acute |
Details
|
Caflanone |
FBL-03G |
Phase 1 Clinical |
Flavocure Biotech Inc |
Pancreatic Neoplasms |
Details
|
EI-1071 |
EI-1071; FB-1071 |
Phase 1 Clinical |
Elixiron Immunotherapeutics Inc |
Giant Cell Tumor of Tendon Sheath; Alzheimer Disease; Nervous System Diseases; Amyotrophic Lateral Sclerosis |
Details
|
SYHA-1817 |
SYHA-1817 |
Phase 1 Clinical |
CSPC Pharmaceutical Group Ltd |
Biliary Tract Neoplasms; Stomach Neoplasms; Carcinoma, Squamous Cell |
Details
|
TT-00420/Atezolizumab |
|
Phase 1 Clinical |
TransThera Sciences (Nanjing) Inc |
Gastrointestinal Neoplasms |
Details
|
BC-006 |
BC-006; BC006 |
Phase 1 Clinical |
Dragonboat Biopharmaceutical |
Solid tumours; Giant Cell Tumor of Tendon Sheath |
Details
|
AGX-0073 |
AGX-0073 |
Phase 1 Clinical |
Shanghai Aojian Biological Technology Co Ltd |
Solid tumours |
Details
|
SYHA-1813 |
SYHA1813 |
Phase 1 Clinical |
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Runshi Pharmaceutical Technology Co Ltd |
Giant Cell Tumor of Tendon Sheath; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Gliosarcoma; Colorectal Neoplasms; Brain metastases; Thyroid Neoplasms; Lung Neoplasms; Glioma |
Details
|