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HEK293/Human Glypican-3 (GPC3) Stable Cell Line

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  • Description
    The HEK293/Human Glypican-3 (GPC3) Stable Cell Line was engineered to express the receptor full length human GPC3 (Gene ID: 2719), used to mimic cancer target cells. Surface expression of Human GPC3 was confirmed by flow cytometry.
  • Application

    • Useful for cell-based GPC3 binding assay

  • Growth Properties
    Adherent
  • Selection Marker
    Puromycin (2 μg/mL)
  • Culture Medium
    DMEM medium + 10% FBS
  • Freeze Medium
    Serum-free cell cryopreservation medium
  • Quantity
    1 vial contains at least 5×10^6 cells in 1 mL serum-free cryopreservation medium
  • Storage
    Frozen in liquid nitrogen.
  • Mycoplasma Testing
    Negative
  • Sterility Testing
    Negative
  • Instructions for Use
    See data sheet for detailed culturing and assay protocol.
Receptor Assay
 Glypican 3 FACS

Expression analysis of human GPC3 on HEK293/Human Glypican-3 (GPC3) Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human Glypican-3 (GPC3) Stable Cell Line or negative control cell using PE-labeled anti-human GPC3 antibody.

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  • Background
    Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
  • Permits & Restrictions
    This cell line is provided for research use only. It is not intended for any animal or human therapeutic use, any human or animal consumption, or any diagnostic use. You are not allowed to share, distribute, sell, modify, sublicense, or otherwise make this cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. AcroBiosystems does not warrant the suitability of this cell line for any particular use, and does not accept any liability in connection with the handling or use of this cell line.
  • Clinical and Translational Updates

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ETA des produits en stock: 2 jours ouvrables

Price(EUR) : €3540.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:36 Details
  • Latest Research Phase:Phase 2 Clinical

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