Talabostat |
PT-100; BXCL-701 |
Phase 2 Clinical |
Point Therapeutics |
Neuroblastoma; Adenocarcinoma; Melanoma; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms, Germ Cell and Embryonal; Carcinoma, Small Cell; Carcinoma, Pancreatic Ductal; Lung Neoplasms; Leukemia, Myeloid, Acute; Prostatic Neoplasms; Liver Neoplasms; Brain Neoplasms; Sarcoma; Neuroendocrine Tumors; Central Nervous System Neoplasms; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Skin Neoplasms; Myelodysplastic Syndromes; Kidney Neoplasms; Solid tumours; Ovarian Neoplasms |
Details
|
[18F]FAPI-74 |
FAPI-74; [18F]FAPI-74 |
Phase 2 Clinical |
Sofie |
Biliary Tract Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms |
Details
|
68Ga-FAP-2286 |
68Ga-FAP-2286; 68-Ga-FAP-2286 |
Phase 2 Clinical |
3B Pharmaceuticals GmbH |
Solid tumours; Neoplasm Metastasis |
Details
|
68Ga-FAPI-46 |
[68Ga]FAPI-46; 68Ga-FAPI-46 |
Phase 2 Clinical |
Karolinska University Hospital |
Pancreatic Neoplasms; Alveolitis, Extrinsic Allergic; Pneumoconiosis; Carcinoma, Pancreatic Ductal; Bile Duct Neoplasms; Lung Diseases, Interstitial; Pulmonary Fibrosis; Neoplasms; Carcinoma, Ovarian Epithelial; Adenomatous Polyposis Coli; Pneumonia; Esophageal Neoplasms; Metabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Interstitial Pneumonias; Radiation Pneumonitis; Stomach Neoplasms; Ovarian Neoplasms |
Details
|
RO-7122290 |
RO-7122290; RG-7827 |
Phase 2 Clinical |
F. Hoffmann-La Roche Ltd |
Colorectal Neoplasms |
Details
|
NG-641 |
EnAd-FAP-BiTE; EnAd-FAP-Tac; NG-641; NG-aFAP |
Phase 1 Clinical |
Akamis Bio Ltd, University Of Oxford |
Squamous Cell Carcinoma of Head and Neck; Neoplasms, Glandular and Epithelial; Neoplasm Metastasis |
Details
|
Simlukafusp alfa |
FAP-IL2v; RG-7461; aFAP-IL2v; RO-6874281; FAP-IL2v FP |
Phase 1 Clinical |
F. Hoffmann-La Roche Ltd |
Head and Neck Neoplasms; Solid tumours; Carcinoma, Renal Cell; Esophageal Neoplasms; Breast Neoplasms; Uterine Cervical Neoplasms; Melanoma |
Details
|
Nectin4/FAP-targeted CAR-T cell therapy (The Sixth Affiliated Hospital of Wenzhou Medical University) |
|
Phase 1 Clinical |
Wenzhou Medical University, The Sixth Affiliated Hospital Of Wenzhou Medical University |
Solid tumours |
Details
|
OMTX-705 |
OMTX-705 |
Phase 1 Clinical |
Oncomatryx Biopharma Sl |
Solid tumours |
Details
|
MP-0310 |
MP-0310; AMG-506 |
Phase 1 Clinical |
Molecular Partners Ag, Amgen Inc |
Solid tumours |
Details
|
68 Ga-OncoFAP-DOTAGA |
68 Ga-OncoFAP |
Phase 1 Clinical |
Blue Earth Diagnostics, Philochem |
Solid tumours |
Details
|
AAA-614 |
AAA-614; FAP-2286 |
Phase 1 Clinical |
Novartis Ag |
Solid tumours |
Details
|
18F-AlF-FAPi-04 |
18F-AlF-FAPi-04 |
Phase 1 Clinical |
Affiliated Hospital Of North Sichuan Medical College |
Solid tumours |
Details
|
177Lu-EB-FAPI(Peking Union Medical College Hospital) |
177Lu-EB-FAPI(Peking Union Medical College Hospital) |
Phase 1 Clinical |
Peking Union Medical College Hospital |
Neoplasm Metastasis |
Details
|
68Ga-FAPI(Peking Union Medical College Hospital) |
68Ga-FAPI(Peking Union Medical College Hospital) |
Phase 1 Clinical |
Peking Union Medical College Hospital |
Neoplasm Metastasis |
Details
|
177Lu-EB-FAPI |
177Lu-EB-FAPI |
Phase 1 Clinical |
Zhejiang University |
Pancreatic Neoplasms; Cholangiocarcinoma |
Details
|
RTX-1363-S |
RTX-1363S; RTX-1363-S |
Phase 1 Clinical |
Ratio Therapeutics Inc |
Stomach Neoplasms; Pancreatic Neoplasms; Breast Neoplasms; Lung Neoplasms |
Details
|
177Lu-DOTA-EB-FAPI |
|
Phase 1 Clinical |
The First Affiliated Hospital Of Xiamen University |
Solid tumours; Adenocarcinoma, Follicular; Thyroid Neoplasms; Thyroid Cancer, Papillary |
Details
|
68Ga/64Cu-FAPI-XT117 |
68Ga/64Cu-FAPI-XT117 |
Phase 1 Clinical |
Pla General Hospital |
Solid tumours |
Details
|
177Lu-LNC1004 |
177Lu-LNC1004; 177Lu-LNC-1004 |
Phase 1 Clinical |
Shanghai Lannacheng Biotechnology Co Ltd |
Solid tumours |
Details
|
68Ga-FAPI-RGD |
68Ga-FAPI-RGD |
Phase 1 Clinical |
Peking Union Medical College Hospital |
Lung Neoplasms |
Details
|
SHR-7367 |
SHR7367; SHR-7367 |
Phase 1 Clinical |
Shanghai Hengrui Pharmaceutical Co Ltd |
Solid tumours; Neoplasms |
Details
|
177Lu-PNT6555(Point Biopharma) |
PNT-6555 |
Phase 1 Clinical |
|
Solid tumours; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Sarcoma; Cholangiocarcinoma; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Melanoma |
Details
|
RO-7300490 |
RO-7300490; RG-6189 |
Phase 1 Clinical |
F. Hoffmann-La Roche Ltd |
Solid tumours; Neoplasms |
Details
|
[90Y] YFAPI-46 |
|
Clinical |
German Cancer Consortium (Dktk), University of Duisburg-Essen |
Solid tumours |
Details
|
3BP-3940 |
3BP-3940 |
Clinical |
Johannes Gutenberg University Of Mainz, 3B Pharmaceuticals GmbH |
Neoplasms |
Details
|
64Cu-LNTH-1363S |
64Cu-LNTH-1363S |
|
|
|
Details
|
177Lu-FAP-2286 |
177Lu-FAP-2286 |
|
3B Pharmaceuticals GmbH |
Solid tumours |
Details
|
Talabostat |
PT-100; BXCL-701 |
Phase 2 Clinical |
Point Therapeutics |
Neuroblastoma; Adenocarcinoma; Melanoma; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms, Germ Cell and Embryonal; Carcinoma, Small Cell; Carcinoma, Pancreatic Ductal; Lung Neoplasms; Leukemia, Myeloid, Acute; Prostatic Neoplasms; Liver Neoplasms; Brain Neoplasms; Sarcoma; Neuroendocrine Tumors; Central Nervous System Neoplasms; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Skin Neoplasms; Myelodysplastic Syndromes; Kidney Neoplasms; Solid tumours; Ovarian Neoplasms |
Details
|
[18F]FAPI-74 |
FAPI-74; [18F]FAPI-74 |
Phase 2 Clinical |
Sofie |
Biliary Tract Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms |
Details
|
68Ga-FAP-2286 |
68Ga-FAP-2286; 68-Ga-FAP-2286 |
Phase 2 Clinical |
3B Pharmaceuticals GmbH |
Solid tumours; Neoplasm Metastasis |
Details
|
68Ga-FAPI-46 |
[68Ga]FAPI-46; 68Ga-FAPI-46 |
Phase 2 Clinical |
Karolinska University Hospital |
Pancreatic Neoplasms; Alveolitis, Extrinsic Allergic; Pneumoconiosis; Carcinoma, Pancreatic Ductal; Bile Duct Neoplasms; Lung Diseases, Interstitial; Pulmonary Fibrosis; Neoplasms; Carcinoma, Ovarian Epithelial; Adenomatous Polyposis Coli; Pneumonia; Esophageal Neoplasms; Metabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Interstitial Pneumonias; Radiation Pneumonitis; Stomach Neoplasms; Ovarian Neoplasms |
Details
|
RO-7122290 |
RO-7122290; RG-7827 |
Phase 2 Clinical |
F. Hoffmann-La Roche Ltd |
Colorectal Neoplasms |
Details
|
NG-641 |
EnAd-FAP-BiTE; EnAd-FAP-Tac; NG-641; NG-aFAP |
Phase 1 Clinical |
Akamis Bio Ltd, University Of Oxford |
Squamous Cell Carcinoma of Head and Neck; Neoplasms, Glandular and Epithelial; Neoplasm Metastasis |
Details
|
Simlukafusp alfa |
FAP-IL2v; RG-7461; aFAP-IL2v; RO-6874281; FAP-IL2v FP |
Phase 1 Clinical |
F. Hoffmann-La Roche Ltd |
Head and Neck Neoplasms; Solid tumours; Carcinoma, Renal Cell; Esophageal Neoplasms; Breast Neoplasms; Uterine Cervical Neoplasms; Melanoma |
Details
|
Nectin4/FAP-targeted CAR-T cell therapy (The Sixth Affiliated Hospital of Wenzhou Medical University) |
|
Phase 1 Clinical |
Wenzhou Medical University, The Sixth Affiliated Hospital Of Wenzhou Medical University |
Solid tumours |
Details
|
OMTX-705 |
OMTX-705 |
Phase 1 Clinical |
Oncomatryx Biopharma Sl |
Solid tumours |
Details
|
MP-0310 |
MP-0310; AMG-506 |
Phase 1 Clinical |
Molecular Partners Ag, Amgen Inc |
Solid tumours |
Details
|
68 Ga-OncoFAP-DOTAGA |
68 Ga-OncoFAP |
Phase 1 Clinical |
Blue Earth Diagnostics, Philochem |
Solid tumours |
Details
|
AAA-614 |
AAA-614; FAP-2286 |
Phase 1 Clinical |
Novartis Ag |
Solid tumours |
Details
|
18F-AlF-FAPi-04 |
18F-AlF-FAPi-04 |
Phase 1 Clinical |
Affiliated Hospital Of North Sichuan Medical College |
Solid tumours |
Details
|
177Lu-EB-FAPI(Peking Union Medical College Hospital) |
177Lu-EB-FAPI(Peking Union Medical College Hospital) |
Phase 1 Clinical |
Peking Union Medical College Hospital |
Neoplasm Metastasis |
Details
|
68Ga-FAPI(Peking Union Medical College Hospital) |
68Ga-FAPI(Peking Union Medical College Hospital) |
Phase 1 Clinical |
Peking Union Medical College Hospital |
Neoplasm Metastasis |
Details
|
177Lu-EB-FAPI |
177Lu-EB-FAPI |
Phase 1 Clinical |
Zhejiang University |
Pancreatic Neoplasms; Cholangiocarcinoma |
Details
|
RTX-1363-S |
RTX-1363S; RTX-1363-S |
Phase 1 Clinical |
Ratio Therapeutics Inc |
Stomach Neoplasms; Pancreatic Neoplasms; Breast Neoplasms; Lung Neoplasms |
Details
|
177Lu-DOTA-EB-FAPI |
|
Phase 1 Clinical |
The First Affiliated Hospital Of Xiamen University |
Solid tumours; Adenocarcinoma, Follicular; Thyroid Neoplasms; Thyroid Cancer, Papillary |
Details
|
68Ga/64Cu-FAPI-XT117 |
68Ga/64Cu-FAPI-XT117 |
Phase 1 Clinical |
Pla General Hospital |
Solid tumours |
Details
|
177Lu-LNC1004 |
177Lu-LNC1004; 177Lu-LNC-1004 |
Phase 1 Clinical |
Shanghai Lannacheng Biotechnology Co Ltd |
Solid tumours |
Details
|
68Ga-FAPI-RGD |
68Ga-FAPI-RGD |
Phase 1 Clinical |
Peking Union Medical College Hospital |
Lung Neoplasms |
Details
|
SHR-7367 |
SHR7367; SHR-7367 |
Phase 1 Clinical |
Shanghai Hengrui Pharmaceutical Co Ltd |
Solid tumours; Neoplasms |
Details
|
177Lu-PNT6555(Point Biopharma) |
PNT-6555 |
Phase 1 Clinical |
|
Solid tumours; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Sarcoma; Cholangiocarcinoma; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Melanoma |
Details
|
RO-7300490 |
RO-7300490; RG-6189 |
Phase 1 Clinical |
F. Hoffmann-La Roche Ltd |
Solid tumours; Neoplasms |
Details
|
[90Y] YFAPI-46 |
|
Clinical |
German Cancer Consortium (Dktk), University of Duisburg-Essen |
Solid tumours |
Details
|
3BP-3940 |
3BP-3940 |
Clinical |
Johannes Gutenberg University Of Mainz, 3B Pharmaceuticals GmbH |
Neoplasms |
Details
|
64Cu-LNTH-1363S |
64Cu-LNTH-1363S |
|
|
|
Details
|
177Lu-FAP-2286 |
177Lu-FAP-2286 |
|
3B Pharmaceuticals GmbH |
Solid tumours |
Details
|