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Your Position: Accueil > Protein > 5-HT2AR > 5HR-H55D3

Human 5-HT2AR Protein (S162K, M164W, S372N), Flag,His Tag (Detergent)

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  • Synonym
    5-HT2A, HTR2A, HTR2, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A
  • Source
    Human 5-HT2AR Protein (S162K, M164W, S372N), Flag,His Tag(5HR-H55D3) is expressed from Baculovirus-Insect cells. It contains AA Asp 2- Ala 265 & Gln 313 - Lys 403 (Accession # P28223-1 (S162K, M164W, S372N)).
    Predicted N-terminus: Asp
  • Molecular Characterization

    This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 55.3 kDa.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    This product is not suitable for cell based experiments due to cytotoxicity of LMNG.
    LMNG and CHS are INDISPENSABLE to keep membrane protein soluble and active, under no circumastance should you remove LMNG and CHS.
    LMNG/CHS buffer (LG-13) is sold separately and not included in protein, and please contact us if you need the buffer.
    If glycerol is not compatible to your application, remove glycerol just before immediate experiment, and NEVER store glycerol-free protein solution.

    Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, LMNG, CHS, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
*The LMNG buffer (Cat. No. LG-13) is sold separately and not included in protein, you can follow this link for product information.
Bioactivity-ELISA
 5-HT2AR ELISA

Immobilized Human 5-HT2AR Protein (S162K, M164W, S372N), Flag,His Tag (Cat. No. 5HR-H55D3) at 5 μg/mL (100 μL/well) can bind Anti-5-HT2AR Antibody with a linear range of 0.02-0.625 μg/mL (QC tested).

  • Background
    This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepres.
  • Clinical and Translational Updates

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