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Rat ALPP Protein, His Tag

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  • Synonym
    PLAP
  • Source
    Rat ALPP Protein, His Tag(ALP-R52H4) is expressed from human 293 cells (HEK293). It contains AA Leu 19 - Ser 501 (Accession # D4ADM6).
    Predicted N-terminus: Leu 19
  • Molecular Characterization
    ALPP Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 54.4 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
ALPP SDS-PAGE

Rat ALPP Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-ELISA
 ALPP ELISA

Immobilized Rat ALPP Protein, His Tag (Cat. No. ALP-R52H4) at 1 μg/mL (100 μL/well) can bind various dilution ratio of Anti-ALPP/ALPG/ALPI Polyclonal Antibody (QC tested).

  • Background
    ALPP is highly expressed in a variety of solid tumors, including ovarian, endometrial, germ cell, non-small cell lung, bladder and gastric cancers.In normal tissues, it is expressed in the placenta and low in lung and reproductive tissues.ALPP is a membrane protein and exits as a homodimer.
  • Clinical and Translational Updates

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Price(EUR) : €380.00

Price(EUR) : €2630.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:1 Details
  • Latest Research Phase:Phase 2 Clinical

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