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Your Position: Accueil > Protein > CEACAM-5 > CE5-R52H3

Rhesus macaque CEACAM-5 / CD66e Protein, His Tag (MALS verified)

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  • Synonym
    CEACAM-5,CD66e,CEA,Meconium antigen 100
  • Source
    Rhesus macaque CEACAM-5 Protein, His Tag(CE5-R52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Gly 685 (Accession # A0A345AMC6-1).
    Predicted N-terminus: Gln 35
  • Molecular Characterization
    CEACAM-5 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 73.7 kDa. The protein migrates as 110-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CEACAM-5 SDS-PAGE

Rhesus macaque CEACAM-5 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
CEACAM-5 MALS images

The purity of Rhesus macaque CEACAM-5 Protein, His Tag (Cat. No. CE5-R52H3) is more than 90% and the molecular weight of this protein is around 225-260 kDa verified by SEC-MALS.

  • Background
    This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
  • Clinical and Translational Updates

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  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:10 Details
  • Latest Research Phase:Phase 3 Clinical

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