Limited Edition Golden Llama is here! Check out how you can get one. Limited Edition Golden Llama is here! Check out how you can get one.
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Human M-CSF Protein, His Tag (Cat. No. MCF-H5247) captured on CM5 Chip via anti-His antibody can bind Human M-CSF R Protein, Fc Tag (Cat. No. CSR-H5258) with an affinity constant of 1.9 nM as determined in SPR assay (Biacore T200) (Routinely tested).
Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Regorafenib | DAST; BAY-73-4506 | Approved | Bayer AG | Stivarga, Resihance | United States | Colorectal Neoplasms | Bayer Healthcare Pharmaceuticals Inc | 2012-09-27 | Fallopian Tube Neoplasms; Osteosarcoma; Sarcoma, Ewing; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Peritoneal Neoplasms; Bone Neoplasms; Bile Duct Neoplasms; Thymoma; Thyroid Neoplasms; Leukemia, Myeloid, Acute; Gastrinoma; Lung Neoplasms; Esophageal adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Melanoma; Gastrointestinal Neoplasms; Somatostatinoma; Adenocarcinoma; Neoplasm Metastasis; Meningioma; Neoplasms; Solid tumours; Ovarian Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Hemangiosarcoma; Carcinoid Tumor; Insulinoma; Carcinoma, Islet Cell; Stomach Neoplasms; Esophageal Neoplasms; Liver Neoplasms; Carcinoma, Transitional Cell; Colonic Neoplasms; Pancreatic Neoplasms; Glioblastoma; Carcinoma, Ovarian Epithelial; Adenoma; Glucagonoma; Carcinoma, Adenoid Cystic; Sarcoma | Details |
Nintedanib Esylate | BIBF-1120 | Approved | C.H. Boehringer Sohn Ag & Co. Kg | Ofev, Vargatef | United States | Idiopathic Pulmonary Fibrosis | Boehringer Ingelheim Gmbh | 2014-10-15 | Lung Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Adenocarcinoma, Clear Cell; systemic sclerosis-associated interstitial lung disease; Colorectal Neoplasms; Peritoneal Neoplasms; Gliosarcoma; Hepatic Insufficiency; Astrocytoma; Genital Neoplasms, Female; Silicosis; Sarcoma; Carcinoma, Squamous Cell; Fallopian Tube Neoplasms; Appendiceal Neoplasms; Leukemia, Myeloid, Acute; Uterine Neoplasms; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Adenocarcinoma; Carcinoma, Endometrioid; Scleroderma, Systemic; Telangiectasia, Hereditary Hemorrhagic; Solid tumours; Rejection of lung transplantation; Carcinoma, Renal Cell; Radiation Pneumonitis; Esophageal Neoplasms; Carcinoid Tumor; Endometrial Stromal Tumors; Idiopathic Pulmonary Fibrosis; Neoplasms; Ovarian Neoplasms; Glioblastoma; Colonic Neoplasms; Small Cell Lung Carcinoma; Pulmonary Fibrosis; Lung Diseases, Interstitial; Oligodendroglioma; Multiple Myeloma; Mesothelioma; Asbestosis; Neuroendocrine Tumors | Details |
pacritinib citrate | SB-1518; ONX-0803 | Approved | S*BIO Pte Ltd, Concert | VONJO | United States | Primary Myelofibrosis | Cti Biopharma Corp | 2022-02-28 | Hepatic Insufficiency; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell; Thrombocythemia, Essential; Sarcoma, Kaposi; Thrombocytopenia; Lymphoma, T-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Leukemia, Myelomonocytic, Juvenile; Lymphoma, T-Cell, Cutaneous; Leukemia, Myeloid, Acute; Waldenstrom Macroglobulinemia; Colorectal Neoplasms; Lymphoproliferative Disorders; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Lymphoma, T-Cell, Peripheral; Castleman Disease; Primary Myelofibrosis; Coronavirus Infections; Lymphoma, Mantle-Cell; Coronavirus Disease 2019 (COVID-19); Hodgkin Disease; Myeloproliferative Disorders; Leukemia, Myelomonocytic, Chronic; Graft vs Host Disease; Myelodysplastic Syndromes; Polycythemia Vera; Lymphoma, B-Cell; Leukemia, Myelogenous, Chronic; Leukemia | Details |
Surufatinib | HMPL-012 | Approved | Hutchison Medipharma Ltd | 苏泰达, SULANDA | Mainland China | Neuroendocrine Tumors | Hutchison Medipharma Ltd | 2020-12-29 | Solid tumours; Biliary Tract Neoplasms; Hematologic Neoplasms; Intestinal Neoplasms; Pancreatic Neoplasms; Pancreatic neuroendocrine tumors (pNET); Neoplasms; Kidney Diseases; Small Cell Lung Carcinoma; Neuroendocrine Tumors; Sarcoma; Bile Duct Neoplasms; Hepatic Insufficiency; Thyroid Neoplasms; Appendiceal Neoplasms; Carcinoma, Neuroendocrine | Details |
Sunitinib Malate | PNU-290940AD; PHA-290940AD; SCAI-003; GB-102; PNU-290940; SU-011248-L-malate salt; PHA-290940; SU-010398; SU-11248 | Approved | Pfizer Inc | 索坦, Sutent | United States | Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors | Cppi Cv | 2006-01-26 | Solid tumours; Fibromatosis, Aggressive; Ovarian Neoplasms; Kidney Neoplasms; Leukemia, Myelogenous, Chronic; Head and Neck Neoplasms; Leiomyosarcoma; Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; HIV Infections; Leukemia, Myeloid, Accelerated Phase; Leukemia; Fibrosarcoma; Teratoma; Liver Neoplasms; Ependymoma; Lymphoma, T-Cell, Peripheral; Intestinal Neoplasms; Histiocytoma, Malignant Fibrous; Carcinoma, Renal Cell; Hemangioblastoma; Carcinoma, Islet Cell; Carcinoma; Pheochromocytoma; Stomach Neoplasms; Pelvic Neoplasms; Esophageal Neoplasms; Leukemia, Hairy Cell; Polycythemia Vera; Abdominal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thoracic Neoplasms; Pancreatic neuroendocrine tumors (pNET); Carcinoma, Ovarian Epithelial; Glioblastoma; Neurofibromatoses; Small Cell Lung Carcinoma; Adenoma, Islet Cell; Carcinoma, Transitional Cell; Pancreatic Neoplasms; Lymphoma, Large B-Cell, Diffuse; Neoplasms; Myelodysplastic Syndromes; Hodgkin Disease; Leukemia, Myelomonocytic, Chronic; Carcinoma, Papil | Details |
Pexidartinib | PLX-3397 | Approved | Daiichi Sankyo Co Ltd | Turalio | United States | Giant Cell Tumor of Tendon Sheath | Daiichi Sankyo Inc | 2019-08-02 | Prostatic Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Neoplasm Metastasis; Leukemia, Myeloid, Acute; Gastrointestinal Stromal Tumors; Colorectal Neoplasms; Neurofibrosarcoma; Giant Cell Tumors; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Neurofibroma, Plexiform; Sarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Solid tumours; Breast Neoplasms; Neoplasms; Arthritis, Rheumatoid; Hodgkin Disease; Glioblastoma; Pancreatic Neoplasms; Synovitis, Pigmented Villonodular; Squamous Cell Carcinoma of Head and Neck; Leukemia, Promyelocytic, Acute; Ovarian Neoplasms; Giant Cell Tumor of Tendon Sheath | Details |
Mirimostim | P-100; CSF-HU | Approved | Jcr Pharmaceuticals Co Ltd | Costilate, Leukoprol | Japan | Neutropenia | Jcr Pharmaceuticals Co Ltd | 1991-01-01 | Neutropenia | Details |
Pazopanib Hydrochloride | GSK-786034; GW-786034B; SB-786034; GW-786034 | Approved | Glaxosmithkline Plc, Novartis Pharma Ag | 维全特, Armala, Votrient, Patorma | United States | Carcinoma, Renal Cell; Sarcoma | Novartis Pharma Ag | 2009-10-19 | Uterine Cervical Diseases; Fallopian Tube Neoplasms; Lung Neoplasms; Uterine Neoplasms; Choriocarcinoma; Lymphoma; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Carcinoma, Mucoepidermoid; Gliosarcoma; Genital Neoplasms, Female; Leukemia, Myeloid, Acute; Peritoneal Neoplasms; Brain Neoplasms; Urethral Neoplasms; Medullary thyroid cancer (MTC); Chondrosarcoma, Extraskeletal Myxoid; Prostatic Neoplasms; Osteosarcoma; Neuroblastoma; Sarcoma; Breast Neoplasms; Carcinoma, Hepatocellular; Uterine Cervical Neoplasms; Breast Neoplasms, Male; Neoplasm Metastasis; von Hippel-Lindau Disease; Thyroid Cancer, Papillary; Gastrointestinal Neoplasms; Paraganglioma; Endodermal Sinus Tumor; Neoplasms, Germ Cell and Embryonal; Melanoma; Gastrinoma; Macular Degeneration; Carcinoma, Non-Small-Cell Lung; Thyroid Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Small Cell; Carcinoma, Embryonal; Germinoma; Glioma; Carcinoma, Neuroendocrine; Epistaxis; Carcinoma, Ovarian Epithelial; Neoplasms; Squamous Cell Carcinoma of Head a | Details |
Regorafenib | DAST; BAY-73-4506 | Approved | Bayer AG | Stivarga, Resihance | United States | Colorectal Neoplasms | Bayer Healthcare Pharmaceuticals Inc | 2012-09-27 | Fallopian Tube Neoplasms; Osteosarcoma; Sarcoma, Ewing; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Peritoneal Neoplasms; Bone Neoplasms; Bile Duct Neoplasms; Thymoma; Thyroid Neoplasms; Leukemia, Myeloid, Acute; Gastrinoma; Lung Neoplasms; Esophageal adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Melanoma; Gastrointestinal Neoplasms; Somatostatinoma; Adenocarcinoma; Neoplasm Metastasis; Meningioma; Neoplasms; Solid tumours; Ovarian Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Hemangiosarcoma; Carcinoid Tumor; Insulinoma; Carcinoma, Islet Cell; Stomach Neoplasms; Esophageal Neoplasms; Liver Neoplasms; Carcinoma, Transitional Cell; Colonic Neoplasms; Pancreatic Neoplasms; Glioblastoma; Carcinoma, Ovarian Epithelial; Adenoma; Glucagonoma; Carcinoma, Adenoid Cystic; Sarcoma | Details |
Nintedanib Esylate | BIBF-1120 | Approved | C.H. Boehringer Sohn Ag & Co. Kg | Ofev, Vargatef | United States | Idiopathic Pulmonary Fibrosis | Boehringer Ingelheim Gmbh | 2014-10-15 | Lung Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Adenocarcinoma, Clear Cell; systemic sclerosis-associated interstitial lung disease; Colorectal Neoplasms; Peritoneal Neoplasms; Gliosarcoma; Hepatic Insufficiency; Astrocytoma; Genital Neoplasms, Female; Silicosis; Sarcoma; Carcinoma, Squamous Cell; Fallopian Tube Neoplasms; Appendiceal Neoplasms; Leukemia, Myeloid, Acute; Uterine Neoplasms; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Adenocarcinoma; Carcinoma, Endometrioid; Scleroderma, Systemic; Telangiectasia, Hereditary Hemorrhagic; Solid tumours; Rejection of lung transplantation; Carcinoma, Renal Cell; Radiation Pneumonitis; Esophageal Neoplasms; Carcinoid Tumor; Endometrial Stromal Tumors; Idiopathic Pulmonary Fibrosis; Neoplasms; Ovarian Neoplasms; Glioblastoma; Colonic Neoplasms; Small Cell Lung Carcinoma; Pulmonary Fibrosis; Lung Diseases, Interstitial; Oligodendroglioma; Multiple Myeloma; Mesothelioma; Asbestosis; Neuroendocrine Tumors | Details |
pacritinib citrate | SB-1518; ONX-0803 | Approved | S*BIO Pte Ltd, Concert | VONJO | United States | Primary Myelofibrosis | Cti Biopharma Corp | 2022-02-28 | Hepatic Insufficiency; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell; Thrombocythemia, Essential; Sarcoma, Kaposi; Thrombocytopenia; Lymphoma, T-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Leukemia, Myelomonocytic, Juvenile; Lymphoma, T-Cell, Cutaneous; Leukemia, Myeloid, Acute; Waldenstrom Macroglobulinemia; Colorectal Neoplasms; Lymphoproliferative Disorders; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Lymphoma, T-Cell, Peripheral; Castleman Disease; Primary Myelofibrosis; Coronavirus Infections; Lymphoma, Mantle-Cell; Coronavirus Disease 2019 (COVID-19); Hodgkin Disease; Myeloproliferative Disorders; Leukemia, Myelomonocytic, Chronic; Graft vs Host Disease; Myelodysplastic Syndromes; Polycythemia Vera; Lymphoma, B-Cell; Leukemia, Myelogenous, Chronic; Leukemia | Details |
Surufatinib | HMPL-012 | Approved | Hutchison Medipharma Ltd | 苏泰达, SULANDA | Mainland China | Neuroendocrine Tumors | Hutchison Medipharma Ltd | 2020-12-29 | Solid tumours; Biliary Tract Neoplasms; Hematologic Neoplasms; Intestinal Neoplasms; Pancreatic Neoplasms; Pancreatic neuroendocrine tumors (pNET); Neoplasms; Kidney Diseases; Small Cell Lung Carcinoma; Neuroendocrine Tumors; Sarcoma; Bile Duct Neoplasms; Hepatic Insufficiency; Thyroid Neoplasms; Appendiceal Neoplasms; Carcinoma, Neuroendocrine | Details |
Sunitinib Malate | PNU-290940AD; PHA-290940AD; SCAI-003; GB-102; PNU-290940; SU-011248-L-malate salt; PHA-290940; SU-010398; SU-11248 | Approved | Pfizer Inc | 索坦, Sutent | United States | Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors | Cppi Cv | 2006-01-26 | Solid tumours; Fibromatosis, Aggressive; Ovarian Neoplasms; Kidney Neoplasms; Leukemia, Myelogenous, Chronic; Head and Neck Neoplasms; Leiomyosarcoma; Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; HIV Infections; Leukemia, Myeloid, Accelerated Phase; Leukemia; Fibrosarcoma; Teratoma; Liver Neoplasms; Ependymoma; Lymphoma, T-Cell, Peripheral; Intestinal Neoplasms; Histiocytoma, Malignant Fibrous; Carcinoma, Renal Cell; Hemangioblastoma; Carcinoma, Islet Cell; Carcinoma; Pheochromocytoma; Stomach Neoplasms; Pelvic Neoplasms; Esophageal Neoplasms; Leukemia, Hairy Cell; Polycythemia Vera; Abdominal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thoracic Neoplasms; Pancreatic neuroendocrine tumors (pNET); Carcinoma, Ovarian Epithelial; Glioblastoma; Neurofibromatoses; Small Cell Lung Carcinoma; Adenoma, Islet Cell; Carcinoma, Transitional Cell; Pancreatic Neoplasms; Lymphoma, Large B-Cell, Diffuse; Neoplasms; Myelodysplastic Syndromes; Hodgkin Disease; Leukemia, Myelomonocytic, Chronic; Carcinoma, Papil | Details |
Pexidartinib | PLX-3397 | Approved | Daiichi Sankyo Co Ltd | Turalio | United States | Giant Cell Tumor of Tendon Sheath | Daiichi Sankyo Inc | 2019-08-02 | Prostatic Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Neoplasm Metastasis; Leukemia, Myeloid, Acute; Gastrointestinal Stromal Tumors; Colorectal Neoplasms; Neurofibrosarcoma; Giant Cell Tumors; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Neurofibroma, Plexiform; Sarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Solid tumours; Breast Neoplasms; Neoplasms; Arthritis, Rheumatoid; Hodgkin Disease; Glioblastoma; Pancreatic Neoplasms; Synovitis, Pigmented Villonodular; Squamous Cell Carcinoma of Head and Neck; Leukemia, Promyelocytic, Acute; Ovarian Neoplasms; Giant Cell Tumor of Tendon Sheath | Details |
Mirimostim | P-100; CSF-HU | Approved | Jcr Pharmaceuticals Co Ltd | Costilate, Leukoprol | Japan | Neutropenia | Jcr Pharmaceuticals Co Ltd | 1991-01-01 | Neutropenia | Details |
Pazopanib Hydrochloride | GSK-786034; GW-786034B; SB-786034; GW-786034 | Approved | Glaxosmithkline Plc, Novartis Pharma Ag | 维全特, Armala, Votrient, Patorma | United States | Carcinoma, Renal Cell; Sarcoma | Novartis Pharma Ag | 2009-10-19 | Uterine Cervical Diseases; Fallopian Tube Neoplasms; Lung Neoplasms; Uterine Neoplasms; Choriocarcinoma; Lymphoma; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Carcinoma, Mucoepidermoid; Gliosarcoma; Genital Neoplasms, Female; Leukemia, Myeloid, Acute; Peritoneal Neoplasms; Brain Neoplasms; Urethral Neoplasms; Medullary thyroid cancer (MTC); Chondrosarcoma, Extraskeletal Myxoid; Prostatic Neoplasms; Osteosarcoma; Neuroblastoma; Sarcoma; Breast Neoplasms; Carcinoma, Hepatocellular; Uterine Cervical Neoplasms; Breast Neoplasms, Male; Neoplasm Metastasis; von Hippel-Lindau Disease; Thyroid Cancer, Papillary; Gastrointestinal Neoplasms; Paraganglioma; Endodermal Sinus Tumor; Neoplasms, Germ Cell and Embryonal; Melanoma; Gastrinoma; Macular Degeneration; Carcinoma, Non-Small-Cell Lung; Thyroid Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Small Cell; Carcinoma, Embryonal; Germinoma; Glioma; Carcinoma, Neuroendocrine; Epistaxis; Carcinoma, Ovarian Epithelial; Neoplasms; Squamous Cell Carcinoma of Head a | Details |
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Vimseltinib | DCC-3014 | Phase 3 Clinical | Deciphera | Giant Cell Tumor of Tendon Sheath; Synovitis, Pigmented Villonodular; Neoplasms | Details |
Chiauranib | CS-2164; CS2164 | Phase 3 Clinical | Shenzhen Chipscreen Biosciences Co Ltd | Solid tumours; Ovarian Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Small Cell Lung Carcinoma; Sarcoma; Lymphoma, Non-Hodgkin; Carcinoma, Hepatocellular | Details |
Pimicotinib | ABSK-021 | Phase 3 Clinical | ABbisko Therapeutics Co Ltd | Giant Cell Tumor of Tendon Sheath; Solid tumours; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Neoplasms; Graft vs Host Disease; Sarcoma; Lung Neoplasms; Amyotrophic Lateral Sclerosis | Details |
Emactuzumab | RG-7155; 6FY6EI1X8R; RO-5509554 | Phase 3 Clinical | F. Hoffmann-La Roche Ltd | Solid tumours; Head and Neck Neoplasms; Carcinoma; Neoplasms; Prostatic Neoplasms; Testicular Neoplasms; Lymphoma, Non-Hodgkin; Carcinoma, Squamous Cell | Details |
Recombinant human GM-CSF oncolytic herpes simplex virus type 2 (OH2) | BS-001; BS001; oHSV-2; OH-2; OH2 | Phase 3 Clinical | Wuhan Binhui Biotechnology Co Ltd | Central Nervous System Neoplasms; Melanoma; Lymphoma; Lung Neoplasms; Colorectal Neoplasms; Bile Duct Neoplasms; Breast Neoplasms; Sarcoma; Liver Diseases; Solid tumours; Digestive System Neoplasms; Urinary Bladder Neoplasms; Neoplasms; Pancreatic Neoplasms; Esophageal Neoplasms; Liver Neoplasms; Head and Neck Neoplasms | Details |
Tinengotinib | TT-00420; TT 00420; TT00420 | Phase 3 Clinical | TransThera Sciences (Nanjing) Inc | Biliary Tract Neoplasms; Solid tumours; Kidney Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Triple Negative Breast Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Transitional Cell; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Sarcoma; Thyroid Neoplasms; Gallbladder Neoplasms | Details |
LY-3022855 | IMC-CS4; LY-3022855 | Phase 2 Clinical | Eli Lilly And Company | Solid tumours; Pancreatic Neoplasms; Neoplasms; Neoplasm Metastasis; Melanoma | Details |
Simmitinib hydrochloride | SOMCL-15-290 | Phase 2 Clinical | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Solid tumours; Neoplasms; Esophageal Squamous Cell Carcinoma | Details |
NMS-03592088 | NMS-P088; NMS-03592088 | Phase 2 Clinical | Nerviano Medical Sciences Srl | Leukemia, Myelomonocytic, Chronic; Leukemia, Myeloid, Acute | Details |
Cabiralizumab | FPA-008; ONO-4687; BMS-986227 | Phase 2 Clinical | Five Prime Therapeutics Inc | Solid tumours; Head and Neck Neoplasms; Ovarian Neoplasms; Giant Cell Tumor of Tendon Sheath; Lymphoma, T-Cell, Peripheral; Carcinoma, Renal Cell; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Neoplasms; Pancreatic Neoplasms; Arthritis, Rheumatoid; Glioma; Carcinoma, Non-Small-Cell Lung | Details |
Derazantinib | ARQ-087.2HCl; AQ-14741087; ARQ-087; BAL-087 | Phase 2 Clinical | Arqule Inc | Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Carcinoma, Transitional Cell; Cholangiocarcinoma; Urogenital Neoplasms; Carcinoma, Hepatocellular | Details |
HH185 | 3D-185; 3-D185; HH-185; 3D185 | Phase 2 Clinical | ShangHai HaiHe Biopharma Co Ltd, Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Medicilon Inc | Solid tumours; Cholangiocarcinoma | Details |
C-019199 | C019199 | Phase 2 Clinical | Fujian Haixi Pharmaceuticals Co Ltd | Solid tumours | Details |
Edicotinib | PRV-6527; JNJ-244; JNJ-40346527-AAC-G-002; JNJ-40346527; JNJ-527 | Phase 2 Clinical | Johnson & Johnson | Arthritis, Rheumatoid; Hodgkin Disease; Prostatic Neoplasms; Alzheimer Disease; Cognitive Dysfunction; Leukemia, Myeloid, Acute; Crohn Disease | Details |
Sotuletinib | BLZ-945 | Phase 2 Clinical | Novartis Pharma Ag, Celgene Corp | Solid tumours; Amyotrophic Lateral Sclerosis | Details |
Elzovantinib | TPX-0022 | Phase 2 Clinical | Turning Point Therapeutics Inc | Solid tumours; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis | Details |
[11C]CPPC | Phase 2 Clinical | Johns Hopkins University | Post-Acute COVID-19 Syndrome; Amyotrophic Lateral Sclerosis | Details | |
AMB-05X | AMB-05X | Phase 2 Clinical | Amgen Inc | Giant Cell Tumor of Tendon Sheath; Synovitis, Pigmented Villonodular; Idiopathic Pulmonary Fibrosis; Testicular Neoplasms | Details |
Q-702 | Q-702 | Phase 2 Clinical | Vichem Chemie, Max Planck Institute of Biochemistry, Lead Discovery Center GmbH | Solid tumours; Liver Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Neoplasm Metastasis; Uterine Cervical Neoplasms | Details |
PMI-04 | Phase 1 Clinical | Precision Molecular Inc | Nerve Degeneration | Details | |
APL-102 | APL-102; CBT-102 | Phase 1 Clinical | Apollomics Inc | Solid tumours | Details |
Pamufetinib | TAS-115 | Phase 1 Clinical | Taiho Pharmaceutical Co Ltd, Otsuka Pharmaceutical Co Ltd | Neoplasms | Details |
JDB-383 | JDB-383 | Phase 1 Clinical | Shanghai Jiabao Yaoyin Pharmaceutical Technology Co Ltd | Giant Cell Tumor of Tendon Sheath | Details |
HMPL-653 | HMPL-653 | Phase 1 Clinical | Hutchison Medipharma Ltd | Giant Cell Tumor of Tendon Sheath; Solid tumours; Testicular Neoplasms | Details |
ETH-155036 | ETH-155036; ETH155036 | Phase 1 Clinical | Shengke Pharmaceutical (Jiangsu) Co Ltd | Myelodysplastic Syndromes; Leukemia, Myeloid, Acute | Details |
Caflanone | FBL-03G | Phase 1 Clinical | Flavocure Biotech Inc | Pancreatic Neoplasms | Details |
EI-1071 | EI-1071; FB-1071 | Phase 1 Clinical | Elixiron Immunotherapeutics Inc | Giant Cell Tumor of Tendon Sheath; Alzheimer Disease; Nervous System Diseases; Amyotrophic Lateral Sclerosis | Details |
SYHA-1817 | SYHA-1817 | Phase 1 Clinical | CSPC Pharmaceutical Group Ltd | Biliary Tract Neoplasms; Stomach Neoplasms; Carcinoma, Squamous Cell | Details |
TT-00420/Atezolizumab | Phase 1 Clinical | TransThera Sciences (Nanjing) Inc | Gastrointestinal Neoplasms | Details | |
BC-006 | BC-006; BC006 | Phase 1 Clinical | Dragonboat Biopharmaceutical | Solid tumours; Giant Cell Tumor of Tendon Sheath | Details |
AGX-0073 | AGX-0073 | Phase 1 Clinical | Shanghai Aojian Biological Technology Co Ltd | Solid tumours | Details |
SYHA-1813 | SYHA1813 | Phase 1 Clinical | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Runshi Pharmaceutical Technology Co Ltd | Giant Cell Tumor of Tendon Sheath; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Gliosarcoma; Colorectal Neoplasms; Brain metastases; Thyroid Neoplasms; Lung Neoplasms; Glioma | Details |
Vimseltinib | DCC-3014 | Phase 3 Clinical | Deciphera | Giant Cell Tumor of Tendon Sheath; Synovitis, Pigmented Villonodular; Neoplasms | Details |
Chiauranib | CS-2164; CS2164 | Phase 3 Clinical | Shenzhen Chipscreen Biosciences Co Ltd | Solid tumours; Ovarian Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Small Cell Lung Carcinoma; Sarcoma; Lymphoma, Non-Hodgkin; Carcinoma, Hepatocellular | Details |
Pimicotinib | ABSK-021 | Phase 3 Clinical | ABbisko Therapeutics Co Ltd | Giant Cell Tumor of Tendon Sheath; Solid tumours; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Neoplasms; Graft vs Host Disease; Sarcoma; Lung Neoplasms; Amyotrophic Lateral Sclerosis | Details |
Emactuzumab | RG-7155; 6FY6EI1X8R; RO-5509554 | Phase 3 Clinical | F. Hoffmann-La Roche Ltd | Solid tumours; Head and Neck Neoplasms; Carcinoma; Neoplasms; Prostatic Neoplasms; Testicular Neoplasms; Lymphoma, Non-Hodgkin; Carcinoma, Squamous Cell | Details |
Recombinant human GM-CSF oncolytic herpes simplex virus type 2 (OH2) | BS-001; BS001; oHSV-2; OH-2; OH2 | Phase 3 Clinical | Wuhan Binhui Biotechnology Co Ltd | Central Nervous System Neoplasms; Melanoma; Lymphoma; Lung Neoplasms; Colorectal Neoplasms; Bile Duct Neoplasms; Breast Neoplasms; Sarcoma; Liver Diseases; Solid tumours; Digestive System Neoplasms; Urinary Bladder Neoplasms; Neoplasms; Pancreatic Neoplasms; Esophageal Neoplasms; Liver Neoplasms; Head and Neck Neoplasms | Details |
Tinengotinib | TT-00420; TT 00420; TT00420 | Phase 3 Clinical | TransThera Sciences (Nanjing) Inc | Biliary Tract Neoplasms; Solid tumours; Kidney Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Triple Negative Breast Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Transitional Cell; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Sarcoma; Thyroid Neoplasms; Gallbladder Neoplasms | Details |
LY-3022855 | IMC-CS4; LY-3022855 | Phase 2 Clinical | Eli Lilly And Company | Solid tumours; Pancreatic Neoplasms; Neoplasms; Neoplasm Metastasis; Melanoma | Details |
Simmitinib hydrochloride | SOMCL-15-290 | Phase 2 Clinical | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Solid tumours; Neoplasms; Esophageal Squamous Cell Carcinoma | Details |
NMS-03592088 | NMS-P088; NMS-03592088 | Phase 2 Clinical | Nerviano Medical Sciences Srl | Leukemia, Myelomonocytic, Chronic; Leukemia, Myeloid, Acute | Details |
Cabiralizumab | FPA-008; ONO-4687; BMS-986227 | Phase 2 Clinical | Five Prime Therapeutics Inc | Solid tumours; Head and Neck Neoplasms; Ovarian Neoplasms; Giant Cell Tumor of Tendon Sheath; Lymphoma, T-Cell, Peripheral; Carcinoma, Renal Cell; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Neoplasms; Pancreatic Neoplasms; Arthritis, Rheumatoid; Glioma; Carcinoma, Non-Small-Cell Lung | Details |
Derazantinib | ARQ-087.2HCl; AQ-14741087; ARQ-087; BAL-087 | Phase 2 Clinical | Arqule Inc | Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Carcinoma, Transitional Cell; Cholangiocarcinoma; Urogenital Neoplasms; Carcinoma, Hepatocellular | Details |
HH185 | 3D-185; 3-D185; HH-185; 3D185 | Phase 2 Clinical | ShangHai HaiHe Biopharma Co Ltd, Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Medicilon Inc | Solid tumours; Cholangiocarcinoma | Details |
C-019199 | C019199 | Phase 2 Clinical | Fujian Haixi Pharmaceuticals Co Ltd | Solid tumours | Details |
Edicotinib | PRV-6527; JNJ-244; JNJ-40346527-AAC-G-002; JNJ-40346527; JNJ-527 | Phase 2 Clinical | Johnson & Johnson | Arthritis, Rheumatoid; Hodgkin Disease; Prostatic Neoplasms; Alzheimer Disease; Cognitive Dysfunction; Leukemia, Myeloid, Acute; Crohn Disease | Details |
Sotuletinib | BLZ-945 | Phase 2 Clinical | Novartis Pharma Ag, Celgene Corp | Solid tumours; Amyotrophic Lateral Sclerosis | Details |
Elzovantinib | TPX-0022 | Phase 2 Clinical | Turning Point Therapeutics Inc | Solid tumours; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis | Details |
[11C]CPPC | Phase 2 Clinical | Johns Hopkins University | Post-Acute COVID-19 Syndrome; Amyotrophic Lateral Sclerosis | Details | |
AMB-05X | AMB-05X | Phase 2 Clinical | Amgen Inc | Giant Cell Tumor of Tendon Sheath; Synovitis, Pigmented Villonodular; Idiopathic Pulmonary Fibrosis; Testicular Neoplasms | Details |
Q-702 | Q-702 | Phase 2 Clinical | Vichem Chemie, Max Planck Institute of Biochemistry, Lead Discovery Center GmbH | Solid tumours; Liver Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Neoplasm Metastasis; Uterine Cervical Neoplasms | Details |
PMI-04 | Phase 1 Clinical | Precision Molecular Inc | Nerve Degeneration | Details | |
APL-102 | APL-102; CBT-102 | Phase 1 Clinical | Apollomics Inc | Solid tumours | Details |
Pamufetinib | TAS-115 | Phase 1 Clinical | Taiho Pharmaceutical Co Ltd, Otsuka Pharmaceutical Co Ltd | Neoplasms | Details |
JDB-383 | JDB-383 | Phase 1 Clinical | Shanghai Jiabao Yaoyin Pharmaceutical Technology Co Ltd | Giant Cell Tumor of Tendon Sheath | Details |
HMPL-653 | HMPL-653 | Phase 1 Clinical | Hutchison Medipharma Ltd | Giant Cell Tumor of Tendon Sheath; Solid tumours; Testicular Neoplasms | Details |
ETH-155036 | ETH-155036; ETH155036 | Phase 1 Clinical | Shengke Pharmaceutical (Jiangsu) Co Ltd | Myelodysplastic Syndromes; Leukemia, Myeloid, Acute | Details |
Caflanone | FBL-03G | Phase 1 Clinical | Flavocure Biotech Inc | Pancreatic Neoplasms | Details |
EI-1071 | EI-1071; FB-1071 | Phase 1 Clinical | Elixiron Immunotherapeutics Inc | Giant Cell Tumor of Tendon Sheath; Alzheimer Disease; Nervous System Diseases; Amyotrophic Lateral Sclerosis | Details |
SYHA-1817 | SYHA-1817 | Phase 1 Clinical | CSPC Pharmaceutical Group Ltd | Biliary Tract Neoplasms; Stomach Neoplasms; Carcinoma, Squamous Cell | Details |
TT-00420/Atezolizumab | Phase 1 Clinical | TransThera Sciences (Nanjing) Inc | Gastrointestinal Neoplasms | Details | |
BC-006 | BC-006; BC006 | Phase 1 Clinical | Dragonboat Biopharmaceutical | Solid tumours; Giant Cell Tumor of Tendon Sheath | Details |
AGX-0073 | AGX-0073 | Phase 1 Clinical | Shanghai Aojian Biological Technology Co Ltd | Solid tumours | Details |
SYHA-1813 | SYHA1813 | Phase 1 Clinical | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Runshi Pharmaceutical Technology Co Ltd | Giant Cell Tumor of Tendon Sheath; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Gliosarcoma; Colorectal Neoplasms; Brain metastases; Thyroid Neoplasms; Lung Neoplasms; Glioma | Details |
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