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CD8

Brief Information

Name:Cluster of differentiation 8
Target Synonym:CD8 Antigens
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:11
Lastest Research Phase:Phase 3 Clinical

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
FABm003-05 Mouse APC-CY7-Labeled Monoclonal Anti-Human CD8 Antibody, Mouse IgG
ACRO Quality

Part of Bioactivity data

FABm003-05-Cell-based assay
 CD8 FACS

Flow cytometric analysis of Human peripheral blood lymphocytes respectively staining with APC-CY7-Labeled Monoclonal Anti-Human CD8 Antibody Mouse IgG1 (Cat. No. FABm003-05) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 2.5e5 cells in a final volume of 100 µL), compared with isotype control antibody. APC-CY7 signal was used to evaluate the binding activity (QC tested).

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
GRANITE GRANITE-001; GRT-C901/GRT-R902 Phase 3 Clinical Bristol-Myers Squibb Company, Gritstone Bio Inc Esophageal Neoplasms; Stomach Neoplasms; Carcinoma, Transitional Cell; Colonic Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
89Zr-Df-crefmirlimab IAB-22-M2C Phase 3 Clinical Imaginab Inc Solid tumours; Carcinoma, Merkel Cell; Carcinoma, Renal Cell; Multiple Sclerosis; Lymphoma; Leukoencephalopathy, Progressive Multifocal; Melanoma; Carcinoma, Non-Small-Cell Lung Details
RB-0003 RB-0003; BNT-111 Phase 2 Clinical Biontech Se, Tron Melanoma Details
GEN-009 GEN-009 Phase 2 Clinical Genocea Biosciences Inc Skin Melanoma; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Transitional Cell; Carcinoma, Non-Small-Cell Lung Details
VE-800 VE-800 Phase 2 Clinical Vedanta Biosciences Inc Esophageal Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Adenocarcinoma; Melanoma; Neoplasm Metastasis Details
EBViNT Cell (Eutilex) Phase 2 Clinical Eutilex Lymphoma, Extranodal NK-T-Cell Details
ZED88082A ZED88082A Phase 2 Clinical Umcg The University Medical Center Groningen Neoplasms; Neoplasm Metastasis Details
NY-ESO-1-specific autologous CD8+ T-cell therapy (Fred Hutchinson Cancer Research Center) Phase 1 Clinical Fred Hutchinson Cancer Research Center, National Cancer Institute Liposarcoma; Sarcoma, Synovial; Sarcoma Details
Tcrx T cell Therapy(Second Affiliated Hospital School Of Zhejiang University School Of Medicine) Phase 1 Clinical Second Affiliated Hospital School Of Zhejiang University School Of Medicine Esophageal Neoplasms; Stomach Neoplasms Details
SCRI-E2CAR_EGFRtv1 SCRI-E2CAR_EGFRtv1 Phase 1 Clinical Umoja BioPharma Inc Osteosarcoma Details
68-Ga-NODAGA-SNA-006 SNA-006; 68-Ga-NODAGA-SNA-006 Phase 1 Clinical Smartnuclide Biopharma Solid tumours Details
GRANITE GRANITE-001; GRT-C901/GRT-R902 Phase 3 Clinical Bristol-Myers Squibb Company, Gritstone Bio Inc Esophageal Neoplasms; Stomach Neoplasms; Carcinoma, Transitional Cell; Colonic Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
89Zr-Df-crefmirlimab IAB-22-M2C Phase 3 Clinical Imaginab Inc Solid tumours; Carcinoma, Merkel Cell; Carcinoma, Renal Cell; Multiple Sclerosis; Lymphoma; Leukoencephalopathy, Progressive Multifocal; Melanoma; Carcinoma, Non-Small-Cell Lung Details
RB-0003 RB-0003; BNT-111 Phase 2 Clinical Biontech Se, Tron Melanoma Details
GEN-009 GEN-009 Phase 2 Clinical Genocea Biosciences Inc Skin Melanoma; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Transitional Cell; Carcinoma, Non-Small-Cell Lung Details
VE-800 VE-800 Phase 2 Clinical Vedanta Biosciences Inc Esophageal Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Adenocarcinoma; Melanoma; Neoplasm Metastasis Details
EBViNT Cell (Eutilex) Phase 2 Clinical Eutilex Lymphoma, Extranodal NK-T-Cell Details
ZED88082A ZED88082A Phase 2 Clinical Umcg The University Medical Center Groningen Neoplasms; Neoplasm Metastasis Details
NY-ESO-1-specific autologous CD8+ T-cell therapy (Fred Hutchinson Cancer Research Center) Phase 1 Clinical Fred Hutchinson Cancer Research Center, National Cancer Institute Liposarcoma; Sarcoma, Synovial; Sarcoma Details
Tcrx T cell Therapy(Second Affiliated Hospital School Of Zhejiang University School Of Medicine) Phase 1 Clinical Second Affiliated Hospital School Of Zhejiang University School Of Medicine Esophageal Neoplasms; Stomach Neoplasms Details
SCRI-E2CAR_EGFRtv1 SCRI-E2CAR_EGFRtv1 Phase 1 Clinical Umoja BioPharma Inc Osteosarcoma Details
68-Ga-NODAGA-SNA-006 SNA-006; 68-Ga-NODAGA-SNA-006 Phase 1 Clinical Smartnuclide Biopharma Solid tumours Details

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