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Your Position: Accueil > Antibody > CD8 > FABm003-05

APC-CY7-Labeled Monoclonal Anti-Human CD8 Antibody, Mouse IgG

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  • Application
    Flow Cytometry (Evaluation of the expression of CD8 on Human cells).
  • Species
    Mouse
  • Isotype
    Mouse IgG
  • Specificity
    This product is a specific antibody specifically reacts with CD8 protein.
  • Reactivity

    Human

  • Conjugate

    APC-CY7

    Excitation Wavelength: 637 nm

    Emission Wavelength: 780 nm

  • Recommended Dilution
    1:20
  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, 0.2% BSA, 0.03% Proclin 300, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
Bioactivity-FACS
 CD8 FACS

Flow cytometric analysis of Human peripheral blood lymphocytes respectively staining with APC-CY7-Labeled Monoclonal Anti-Human CD8 Antibody Mouse IgG1 (Cat. No. FABm003-05) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 2.5e5 cells in a final volume of 100 µL), compared with isotype control antibody. APC-CY7 signal was used to evaluate the binding activity (QC tested).

  • Background
    CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
  • Clinical and Translational Updates

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ETA des produits en stock: 2 jours ouvrables

Price(EUR) : €550.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:11 Details
  • Latest Research Phase:Phase 3 Clinical

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