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2e5 of 293 cells overexpressing human CD24 were stained with 100μL of 1:10 dilution of PE-Labeled Human Siglec-10 Protein, His Tag(recommended for neutralizing assay)(Cat. No. SI0-HP2E5)and negative control protein respectively , washed and analyzed with FACS (QC tested).
Loaded Human CD32a (R167), His Tag (Cat. No. CDA-H5221) on HIS1K Biosensor, can bind Human Siglec-10, Fc (L118A, G120A, E201A) Tag (Cat. No. SI0-H5255) with an affinity constant of 37.5 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Efprezimod alfa | CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 | Phase 3 Clinical | Oncoimmune Inc | Solid tumours; Hematopoietic stem cell transplantation (HSCT); Leukemia; HIV Infections; Graft vs Host Disease; Myelodysplastic Syndromes; Coronavirus Disease 2019 (COVID-19); Precursor Cell Lymphoblastic Leukemia-Lymphoma; Dyslipidemias; Leukemia, Myeloid, Acute; Melanoma | Details |
EXO-CD24 | Phase 2 Clinical | Tel-Aviv Sourasky Medical Center, Nano24med | Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult | Details | |
AI-071 | AI-071 | Phase 1 Clinical | Oncoimmune-Guangzhou | Neoplasms; Coronavirus Disease 2019 (COVID-19) | Details |
ONC-841 | ONC-841 | Phase 1 Clinical | Oncoimmune-Guangzhou | Solid tumours; Neoplasms | Details |
Efprezimod alfa | CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 | Phase 3 Clinical | Oncoimmune Inc | Solid tumours; Hematopoietic stem cell transplantation (HSCT); Leukemia; HIV Infections; Graft vs Host Disease; Myelodysplastic Syndromes; Coronavirus Disease 2019 (COVID-19); Precursor Cell Lymphoblastic Leukemia-Lymphoma; Dyslipidemias; Leukemia, Myeloid, Acute; Melanoma | Details |
EXO-CD24 | Phase 2 Clinical | Tel-Aviv Sourasky Medical Center, Nano24med | Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult | Details | |
AI-071 | AI-071 | Phase 1 Clinical | Oncoimmune-Guangzhou | Neoplasms; Coronavirus Disease 2019 (COVID-19) | Details |
ONC-841 | ONC-841 | Phase 1 Clinical | Oncoimmune-Guangzhou | Solid tumours; Neoplasms | Details |
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