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Your Position: Accueil > Protein > Mucin-1 > MU1-C52H5

Cynomolgus Mucin-1 / MUC-1 Protein, His Tag

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  • Synonyme
    Mucin 1,MUC1,CD227,EMA,H23AG,KL-6,MAM6,MUC-1,SEC,MUC-1,X,MUC1,ZD,PEM,PEMT,PUM,CA15-3,Episialin
  • Source
    Cynomolgus Mucin-1, His Tag (MU1-C52H5) is expressed from human 293 cells (HEK293). It contains AA Leu 254 - Gly 373 (Accession # XP_005541632.1).
  • Caractérisation moléculaire
    Online(Leu 254 - Gly 373) XP_005541632.1

    This protein carries a polyhistidine tag at the C-terminus. The mature form of Mucin-1 is a non-covalent heterodimeric complex with the proteolytically cleaved partial α and partial β chain. Each partial α and partial β chain has a calculated MW of 7.2 kDa (partial α chain) and 8.3 kDa (partial β chain). The protein migrates as 14 kDa (uncleaved), 12 kDa (partial α chain) and 11 kDa (partial β chain) under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxine
    Less than 1.0 EU per μg by the LAL method.
  • Pureté

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 . Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Stockage:

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Cynomolgus Mucin-1, His Tag (Cat. No. MU1-C52H5) SDS-PAGE gel

Cynomolgus Mucin-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • CONTEXTE
    Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(EUR) : €350.00

Price(EUR) : €2570.00

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