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EGF R

Brief Information

Name:Epidermal growth factor receptor erbB1
Target Synonym:Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog),Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian),Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog,Epidermal Growth Factor Receptor Tyrosine Kinase Domain,Cell Proliferation-Inducing Protein 61,Cell Growth Inhibiting Protein 40,EC 2.7.10.1,NISBD2,PIG61,MENA,EC:2.7.10.1,EC 2.7.10,Receptor tyrosine-protein kinase erbB-1,Proto-oncogene c-ErbB-1,Epidermal growth factor recep
Number of Launched Drugs:31
Number of Drugs in Clinical Trials:169
Lastest Research Phase:Approved

Product ListCompare or Buy

Cat . Non Espèces Description du produit Structure Pureté Caractéristique
CHEK-ATP148 Human HEK293/Human EGF R Stable Cell Line
EGR-M82E3 Mouse Biotinylated Mouse EGF R Protein, His,Avitag™ (MALS verified)
EGR-M82E3-structure
EGR-M82E3-sds
EGR-M82F3 Mouse Biotinylated Mouse EGF R Protein, Fc,Avitag™ (MALS verified)
EGR-M82F3-structure
EGR-M82F3-sds
EGR-M5257 Mouse Mouse EGF R Protein, Fc Tag (MALS verified)
EGR-M5257-structure
EGR-M5257-sds
EGR-HA2H8 Human APC-Labeled Human EGF R Protein, His TagStar Staining
EGR-HP2H7 Human PE-Labeled Human EGF R Protein, His TagStar Staining
EGR-R52H7 Rabbit Rabbit EGF R Protein, His Tag (MALS verified)
EGR-R52H7-structure
EGR-R52H7-sds
EGR-H82F8 Human Biotinylated Human EGF R Protein, Fc,Avitag™ (MALS verified)
EGR-H82F8-structure
EGR-H82F8-sds
EGR-HF256 Human FITC-Labeled Human EGF R Protein, Fc Tag
EGR-HF256-structure
EGR-HF256-sds
EGR-H5259 Human Human EGF R Protein, Llama IgG2b Fc Tag, low endotoxin (MALS verified)
EGR-H5259-structure
EGR-H5259-sds
EGR-HP2E3 Human PE-Labeled Human EGF R Protein, His Tag (Site-specific conjugation)
EGR-HP2E3-structure
MBE-K012 Human Human EGFR-coupled Magnetic Beads
EGR-HF2H5 Human FITC-Labeled Human EGF R Protein, His Tag
EGR-HF2H5-structure
EGR-HF2H5-sds
EGR-H522a Human Human EGF R Protein, His Tag, low endotoxin (MALS verified)
EGR-H522a-structure
EGR-H522a-sds
EGR-H82E3 Human Biotinylated Human EGF R Protein, His,Avitag™ (MALS verified)
EGR-H82E3-structure
EGR-H82E3-sds
EGR-C5252 Rhesus macaque Rhesus macaque EGF R Protein, Fc Tag (MALS verified)
EGR-C5252-structure
EGR-C5252-sds
EGR-C52H1 Rhesus macaque Rhesus macaque EGF R Protein, His Tag (MALS verified)
EGR-C52H1-structure
EGR-C52H1-sds
EGR-M5224 Mouse Mouse EGF R Protein, His Tag (MALS verified)
EGR-M5224-structure
EGR-M5224-sds
EGR-H5252 Human Human EGF R Protein, Fc Tag (MALS verified)
EGR-H5252-structure
EGR-H5252-sds
EGR-H5222 Human Human EGF R Protein, His Tag (MALS verified)
EGR-H5222-structure
EGR-H5222-sds
ACRO Quality

Part of Bioactivity data

EGR-HA2H8-Cell-based assay
 EGF R CAR_T

5e5 of anti-EGFR CAR-293 cells were stained with 100 μL of 1:50 dilution (2 μL stock solution in 100 μL FACS buffer) of APC-Labeled Human EGF R Protein, His Tag (Cat. No. EGR-HA2H8) and negative control protein respectively (Fig. C and B), and non-transfected 293 cells were used as a control (Fig. A). APC signal was used to evaluate the binding activity (QC tested).

EGR-H522a-SPR
 EGF R SPR

Immobilized Erbitux on CM5 Chip via anti-human Fc IgG, can bind Human EGF R, His Tag, low endotoxin (Cat.No. EGR-H522a) with an affinity constant of 0.492 nM as determined in SPR assay (Biacore T200) (Routinely tested).

EGR-H522a-SPR
 EGF R SPR

Human EGF R, His Tag, low endotoxin (Cat. No. EGR-H522a) captured on CM5 Chip via anti-His antibody can bind Human EGF, Mouse IgG2a Fc Tag (Cat. No. EGF-H525b) with an affinity constant of 2.76 nM as determined in SPR assay (Biacore T200) (Routinely tested).

Synonym Name

EGFR,ERBB,ERBB1,HER1,PIG61,mENA

Background

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Osimertinib Mesylate AZD-9291; RDL94R2A16; AZD-9291 Mesylate; AZD9291 Approved Astrazeneca Plc 泰瑞沙, Tagrisso United States Carcinoma, Non-Small-Cell Lung Astrazeneca Pharmaceutical Co Ltd 2015-11-13 Uterine Neoplasms; Urinary Bladder Neoplasms; Multiple Myeloma; Prostatic Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Meningeal Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Brain metastases; Adenocarcinoma of Lung; Endometrial Neoplasms; Thyroid Neoplasms; Carcinoma, Squamous Cell; Lymphoma; Glioma; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Adenocarcinoma; Melanoma; Esophageal Neoplasms; Liver Neoplasms; Head and Neck Neoplasms; Neoplasm, Residual; Ovarian Neoplasms; Hematologic Neoplasms; Carcinoma, Renal Cell; Stomach Neoplasms; Rectal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Solid tumours; Neoplasms; Glioblastoma; Colonic Neoplasms; Carcinoma, Transitional Cell; Carcinoma, Ovarian Epithelial; Skin Neoplasms; Small Cell Lung Carcinoma; Pancreatic Neoplasms Details
PX-070101 PX-070101 Approved Praxis Pharmaceuticals Colombia Diabetic Foot Praxis Pharmaceuticals 2015-07-01 Diabetic Foot Details
Cetuximab sarotalocan RM-1929; ASP-1929 Approved Aspyrian Therapeutics Akalux Japan Head and Neck Neoplasms Rakuten Medical Inc 2020-09-25 Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck Details
Cetuximab IMC-C255; BMS-564717; EMD-271786; C-255; GT-MAB-5.2; ch-225; LY-2939777; NSC-714692 Approved Bristol-Myers Squibb Company, Eli Lilly And Company, Merck Serono 爱必妥, Erbitux United States Colorectal Neoplasms Imclone Gmbh 2004-02-12 Carcinoma, Squamous Cell; Oropharyngeal Neoplasms; Neuralgia; Colorectal Neoplasms; Peritoneal Neoplasms; Glioma; Lung Neoplasms; Endometrial Neoplasms; Esophageal Squamous Cell Carcinoma; Laryngeal Neoplasms; Nasopharyngeal Carcinoma; Adenocarcinoma, Mucinous; Fallopian Tube Neoplasms; Complex Regional Pain Syndromes; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Neoplasm Metastasis; Gastrointestinal Neoplasms; Precancerous Conditions; Glioblastoma; Liver Neoplasms; Head and Neck Neoplasms; Solid tumours; Ovarian Neoplasms; Pain; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms; Neoplastic Cells, Circulating; Neoplasms; Small Cell Lung Carcinoma; Hypopharyngeal Neoplasms; Neoplasms, Squamous Cell; Colonic Neoplasms; Chordoma; Carcinoma, Adenoid Cystic; Sarcoma Details
Afatinib Dimaleate BIBW-2992-MA2; BIBW-2992 Approved C.H. Boehringer Sohn Ag & Co. Kg Gilotrif, Giotrif, Tovok, 吉泰瑞, Tomtovok United States Carcinoma, Non-Small-Cell Lung C.H. Boehringer Sohn Ag & Co. Kg 2013-07-12 Esophageal Squamous Cell Carcinoma; Urethral Neoplasms; Brain Neoplasms; Prostatic Neoplasms; Ureteral Neoplasms; Urologic Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Squamous Cell; Breast Neoplasms; Gallbladder Neoplasms; Uterine Neoplasms; Lymphoma; Glioma; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Neoplasm Metastasis; Small Cell Lung Carcinoma; Head and Neck Neoplasms; Solid tumours; Hematologic Neoplasms; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Stomach Neoplasms; Renal Insufficiency; Neoplasms; Rhabdomyosarcoma; Neuroectodermal Tumors; Glioblastoma; Neoplasms, Squamous Cell; Urinary Bladder Neoplasms; Chordoma; Liver Diseases; Multiple Myeloma Details
Epidermal growth factor biosimilar (RAS Lifesciences) Approved Ras Lifesciences India Ras Lifesciences 2012-10-01 Details
Recombinant epidermal growth factor gel (Pavay Gene Pharmaceutical) Approved Guilin Huanuowei Gene Pharmaceutical Co Ltd 易孚 Mainland China Skin Ulcer; Burns Guilin Huanuowei Gene Pharmaceutical Co Ltd 2002-12-23 Skin Ulcer; Burns Details
Nimotuzumab OSAG-10; KI-0502; KI-0501; DE-766; h-R3; OSAG-101; TheraCIMh-R3; YMB-1000 Approved Center Of Molecular Immunology, Cimym Biosciences BIOMAb-EGFR, TheraCIM, 泰欣生, CIMAher, Theraloc India Head and Neck Neoplasms; Nasopharyngeal Neoplasms null 2006-07-21 Pancreatic neuroendocrine tumors (pNET); Esophageal Diseases; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Glioma; Esophageal Squamous Cell Carcinoma; Colorectal Neoplasms; Nasopharyngeal Carcinoma; Pancreatic Neoplasms; Head and Neck Neoplasms; Nasopharyngeal Diseases; Neoplasms; Nasopharyngeal Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Anus Neoplasms; Solid tumours Details
Recombinant epidermal growth factor (Center for Genetic Engineering and Biotechnology/Praxis Pharmaceuticals) Approved Praxis Pharmaceuticals, Center For Genetic Engineering And Biotechnology Heberprot-P Cuba Diabetic Foot null 2007-09-01 Diabetic Foot Details
Erlotinib Hydrochloride CP-358774-01; RO-0508231; NSC-718781; CP-358774; RG-1415; OSI-774; R-1415 Approved Genentech Inc Tarceva, 特罗凯 EU Pancreatic Neoplasms; Carcinoma, Non-Small-Cell Lung Roche Registration Gmbh 2004-11-18 Head and Neck Neoplasms; Kidney Neoplasms; Cystadenocarcinoma; Solid tumours; Ovarian Neoplasms; Liver Neoplasms; HIV Infections; Adenomatous Polyposis Coli; Neoplasm Recurrence, Local; Ependymoma; Brenner Tumor; Rhabdomyosarcoma; Medulloblastoma; Leukemia, Promyelocytic, Acute; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Cystadenocarcinoma, Mucinous; Anus Neoplasms; Esophageal Neoplasms; Esthesioneuroblastoma, Olfactory; Granuloma, Lethal Midline; Carcinoma, Basal Cell; Rectal Neoplasms; Cystadenocarcinoma, Serous; Polycythemia Vera; Anaplasia; Stomach Neoplasms; Neoplasms; Carcinoma, Transitional Cell; Salivary Gland Neoplasms; Pancreatic Neoplasms; Skin Neoplasms; Small Cell Lung Carcinoma; Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Acute; Colonic Neoplasms; Carcinoma, Ovarian Epithelial; Glioblastoma; Nasopharyngeal Neoplasms; Adenocarcinoma of Lung; Fibrosis; Carcinoma, Verrucous; Liver Cirrhosis; Leukemia, Myelomonocytic, Chronic; Mesothelioma; Urinary Bladder Neoplasms; P Details
Gefitinib ZD-1839 Approved Astrazeneca Plc Iressa, 易瑞沙 Japan Carcinoma, Non-Small-Cell Lung Astrazeneca Pharmaceutical Co Ltd 2002-07-05 Adenocarcinoma, Bronchiolo-Alveolar; Lip Neoplasms; Leukemia, Myeloid, Acute; Glioma; Carcinoma, Squamous Cell; Brain metastases; Lung Neoplasms; Carcinoma, Mucoepidermoid; Astrocytoma; Gliosarcoma; Paranasal Sinus Neoplasms; Colorectal Neoplasms; Gastrinoma; Carcinoma, Adenosquamous; Nasopharyngeal Carcinoma; Medullary thyroid cancer (MTC); Urethral Neoplasms; Brain Neoplasms; Breast Neoplasms; Neoplasms, Germ Cell and Embryonal; Uterine Cervical Neoplasms; Tongue Neoplasms; Thyroid Cancer, Papillary; Somatostatinoma; Carcinoma, Hepatocellular; Breast Neoplasms, Male; Gastrointestinal Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Prostatic Neoplasms; Adenocarcinoma; Endometrial Neoplasms; Fallopian Tube Neoplasms; Thyroid Neoplasms; Neoplasms, Neuroepithelial; Lymphoma; Mouth Neoplasms; Laryngeal Neoplasms; Carcinoma, Renal Cell; Carcinoid Tumor; Parathyroid Neoplasms; Esthesioneuroblastoma, Olfactory; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Basal Cell; Granuloma, Lethal Midlin Details
Brigatinib AP-26113 Approved Ariad Pharmaceuticals Inc Alunbrig, ALUNBRIG United States Carcinoma, Non-Small-Cell Lung Takeda Pharmaceuticals U.S.A. Inc 2017-04-28 Solid tumours; Ependymoma; Carcinoma; Neoplasms; Neurofibromatosis 2; Small Cell Lung Carcinoma; Myofibroma; Lymphoma, Large-Cell, Anaplastic; Brain metastases; Lung Neoplasms; Granuloma, Plasma Cell; Carcinoma, Non-Small-Cell Lung; Sarcoma, Kaposi; Neurilemmoma; Meningioma; Neuroma, Acoustic Details
Recombinant Human Epidermal Growth Factor Derivative (Shenzhen Wastin Genetech) rEGF Approved Shenzhen Watsin Genetech Ltd 金因肽, GeneTime Mainland China Wounds and Injuries Shenzhen Watsin Genetech Ltd 2001-01-01 Wounds and Injuries Details
Nepidermin DWP-401 Approved Daewoong Pharmaceutical Co Ltd Easyef South Korea Alopecia; Diabetic Foot Daewoong Pharmaceutical Co Ltd 2001-01-01 Diabetic Foot; Alopecia; Dry Eye Syndromes Details
Icotinib Hydrochloride BPI-2009H; BPI-2009C Approved Betta Pharmaceuticals Co Ltd 凯美纳, Conmana Mainland China Carcinoma, Non-Small-Cell Lung Betta Pharmaceuticals Co Ltd 2011-06-07 Nasopharyngeal Carcinoma; Neuroma, Acoustic; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Squamous Cell; Lung Neoplasms; Brain metastases; Breast Neoplasms; Carcinoma, Adenosquamous; Solid tumours; Psoriasis; Adenocarcinoma of Lung; Neurofibromatosis 2; Small Cell Lung Carcinoma; Bronchial Neoplasms; Stomach Neoplasms; Esophageal Neoplasms Details
Recombinant human EGF conjugated vaccine Approved Biotech Pharmaceuticals Co Ltd Carcinoma, Non-Small-Cell Lung Details
Recombinant epidermal growth factor (Bharat Biotech) REGEN-D 60; REGEN-D 150 Approved Bharat Biotech International Ltd India Diabetic Foot; Burns Bharat Biotech International Ltd 2005-01-01 Diabetic Foot; Burns Details
Lazertinib YH-25448; JNJ-73841937; JNJ-1937; GNS-1480 Approved Oscotec Inc, Janssen Biotech Inc, Yuhan Corp Leclaza South Korea Carcinoma, Non-Small-Cell Lung Yuhan Corp 2021-01-18 Hepatic Insufficiency; Carcinoma, Non-Small-Cell Lung Details
Recombinant epidermal growth factor biosimilar (Elea) r-hu-EGF Approved Elea Argentina Diabetic Foot; Burns Elea 2015-01-01 Diabetic Foot; Burns Details
Recombinant Human Epidermal Growth Factor Derivative Eye Drops (Shenzhen Wastin Genetech) Approved Shenzhen Watsin Genetech Ltd 金因舒, GeneSoft Mainland China Corneal Diseases Shenzhen Watsin Genetech Ltd 2004-01-21 Corneal Diseases Details
Necitumumab LY-3012211; IMC-11F8 Approved Eli Lilly And Company Portrazza United States Carcinoma, Non-Small-Cell Lung Eli Lilly And Co (Ireland) Ltd 2015-11-24 Solid tumours; Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Sunvozertinib DZD-9008 Approved Dizal (Jiangsu) Pharmaceutical Co Ltd 舒沃哲 Mainland China Carcinoma, Non-Small-Cell Lung Dizal (Jiangsu) Pharmaceutical Co Ltd 2023-08-22 Lymphoma, B-Cell; Hepatic Insufficiency; Lymphoma, Non-Hodgkin; Carcinoma, Non-Small-Cell Lung Details
Panitumumab ABX-0303; E7.6.3; AMG-954; ABX-EGF; ABX-10221 Approved Amgen Inc Vectibix United States Colorectal Neoplasms Amgen Inc 2006-09-27 Small Cell Lung Carcinoma; Exanthema; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms; Neoplasm Metastasis; Glioma; Carcinoma, Squamous Cell; Lung Neoplasms; Adenoma, Pleomorphic; Colorectal Neoplasms; Brain Neoplasms; Prostatic Neoplasms; Colonic Neoplasms; Head and Neck Neoplasms; Pancreatic Neoplasms; Neoplasms; Malignant Carcinoid Syndrome; Salivary Gland Neoplasms; Rectal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Esophageal Neoplasms; Carcinoma; Kidney Neoplasms; Solid tumours Details
Neratinib Maleate CAN-030; PB-272; HKI-272; PF-0528767; WAY-179272 Approved Pfizer Inc Nerlynx, 贺俪安 United States Breast Neoplasms Puma Biotechnology Inc 2017-07-17 Solid tumours; Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Hepatic Insufficiency; Colorectal Neoplasms; Lung Neoplasms; Brain metastases; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung Details
Cetuximab biosimilar (CinnaGen) Approved Cinnagen Iran Colorectal Neoplasms Cinnagen 2017-01-01 Colorectal Neoplasms Details
Lapatinib Ditosylate Hydrate GW-572016; GW-572016F; GW-2016 Approved Glaxosmithkline Plc, Novartis Pharma Ag Tykerb, Tyverb, 泰立沙, Tykerb/Tyverb United States Breast Neoplasms Novartis Pharma Ag 2007-03-13 Laryngeal Neoplasms; Prostatic Neoplasms; Gliosarcoma; Colorectal Neoplasms; Astrocytoma; Bile Duct Neoplasms; Carcinoma, Acinar Cell; Carcinoma, Mucoepidermoid; Endometrial Neoplasms; Neoplasms, Gonadal Tissue; Lung Neoplasms; Carcinoma, Squamous Cell; Glioma; Brain Neoplasms; Gallbladder Neoplasms; Brain metastases; Lymphoma; Uterine Cervical Neoplasms; Adenocarcinoma; Melanoma; Tongue Neoplasms; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Neuroma, Acoustic; Carcinoma, Hepatocellular; Neoplasm Metastasis; Glioblastoma; Ovarian Neoplasms; Ependymoma; Head and Neck Neoplasms; Liver Neoplasms; Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Carcinoma; Abdominal Neoplasms; Salivary Gland Neoplasms; Medulloblastoma; Carcinoma, Verrucous; Neoplasms; Neurofibromatosis 2; Small Cell Lung Carcinoma; Carcinoma, Ovarian Epithelial; Pancreatic Neoplasms; Central Nervous System Neoplasms; Urinary Bladder Neoplasms; Oligodendroglioma; Ca Details
Recombinant epidermal growth factor (Shanghai Haohai ) Approved Shanghai Haohai Biological Technology Co Ltd 康合素 Mainland China Burns Shanghai Haohai Biological Technology Co Ltd 2001-01-01 Burns Details
Amivantamab CNTO-4424; JNJ-61186372; CNTO4424; JNJ-372; JNJ-6372 Approved Genmab A/S, Johnson & Johnson Innovative Medicine RYBREVANT United States Carcinoma, Non-Small-Cell Lung Janssen Biotech Inc 2021-05-21 Esophageal Neoplasms; Stomach Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Adenoid Cystic; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Hepatocellular Details
Recombinant epidermal growth factor drop (Pavay Gene Pharmaceutical) Approved Guilin Huanuowei Gene Pharmaceutical Co Ltd 易贝 Mainland China Corneal Diseases Guilin Huanuowei Gene Pharmaceutical Co Ltd 2002-04-12 Corneal Diseases; Xerophthalmia Details
Pyrotinib Maleate HTI-1001; SHR-1258; BLTN Approved Jiangsu Hengrui Medicine Co Ltd 艾瑞妮 Mainland China Breast Neoplasms Jiangsu Hengrui Medicine Co Ltd 2018-08-12 Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Adenocarcinoma of Lung; Neoplasms; Breast Neoplasms; Bile Duct Neoplasms; Lung Neoplasms; Metastatic breast cancer; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Dacomitinib PF-00299804-03; PF-00299804-3; PF-00299804; PF-299804; PF-299; PF-804 Approved Pfizer Inc Vizimpro United States Carcinoma, Non-Small-Cell Lung Pfizer Inc 2018-09-27 Brain Neoplasms; Adenocarcinoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Penile Neoplasms; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Mouth Neoplasms; Lung Neoplasms; Colorectal Neoplasms; Solid tumours; Liver Diseases; Carcinoma, Large Cell; Glioblastoma; Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Head and Neck Neoplasms Details
Mouse epidermal growth factor (Hangzhou Tianmushan Pharmaceutical) Approved Hangzhou Tianmushan Pharmaceutical Enterprise Co Ltd 一夫 Wounds and Injuries Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
PLB-1004 PLB-1004 Phase 3 Clinical Beijing Avistone Pharmaceuticals Biotechnology Co Ltd Carcinoma, Non-Small-Cell Lung Details
YK-029A YK-029A; YK-209A; YK-209-A; YK-029-A Phase 3 Clinical Hainan Yuekang Biomedicine Co Ltd Drug-Related Side Effects and Adverse Reactions; Carcinoma, Non-Small-Cell Lung Details
Olafertinib CK-101; RX-518; CS-2481; EGFR-IN-3 Phase 3 Clinical Suzhou Neupharma Co Ltd Lung Diseases; Lung Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung Details
Mefatinib Phase 3 Clinical Suzhou Maitai Bio-Technology Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Cetuximab biosimilar (AlphaMab) KN-005 Phase 3 Clinical Suzhou Alphamab Co Ltd Head and Neck Neoplasms; Anus Neoplasms; Urinary Bladder Neoplasms; Colorectal Neoplasms Details
MRG-003 MRG-003; MRG003 Phase 3 Clinical Head and Neck Neoplasms; Solid tumours; Biliary Tract Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Esophageal Neoplasms; Nasopharyngeal Carcinoma; Bile Duct Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
HA121-28 HA121-28; SYHA121-28 Phase 3 Clinical Biliary Tract Neoplasms; Solid tumours; Esophageal Neoplasms; Neoplasms; Medullary thyroid cancer (MTC); Bile Duct Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Nimotuzumab biosimilar (El Kendi Pharmaceuticals Manufacturing) Phase 3 Clinical El Kendi Pharmaceuticals Uterine Cervical Neoplasms Details
Cetuximab biosimilar (AMPO Biotechnology) Phase 3 Clinical Ampo Biotechnology Inc Colorectal Neoplasms Details
Cetuximab biosimilar (R-Pharm) RPH-002 Phase 3 Clinical R-Pharm Head and Neck Neoplasms; Pancreatic Neoplasms Details
QL1203 QL-1203 Phase 3 Clinical Qilu Pharmaceutical Co Ltd Colorectal Neoplasms Details
BEBT-109 BEBT-109 Phase 3 Clinical Guangzhou BeBetter Medicine Technology Co Carcinoma, Non-Small-Cell Lung Details
Immunomodulatory progenitor cell therapy (Celixir) Phase 3 Clinical Celixir Endomyocardial Fibrosis; Cardiomyopathies Details
Izalontamab SI-B001; SI-1X6.4 Phase 3 Clinical Solid tumours; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Neoplasms, Glandular and Epithelial; Triple Negative Breast Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Carcinoma, Non-Small-Cell Lung Details
SKLB-1028 SKLB-1028 Phase 3 Clinical Sichuan University, CSPC Pharmaceutical Group Ltd Solid tumours; Leukemia, Promyelocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute Details
Varlitinib Ditosylate SPS-4370; ASLAN-001; ARRY-334543; ARRY-543; QBT-01 Phase 3 Clinical Array Biopharma Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Neoplasms; Pancreatic Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Bile Duct Neoplasms Details
Becotatug JMT-101 Phase 3 Clinical Shanghai Jmt-Bio Inc Solid tumours; Rectal Neoplasms; Colorectal Neoplasms; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Carcinoma, Non-Small-Cell Lung Details
Izalontamab brengitecan BL-B01D1 Phase 3 Clinical SystImmune Nasopharyngeal Carcinoma; Gastrointestinal Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Metastatic breast cancer; Lung Neoplasms; Esophageal Squamous Cell Carcinoma; Colorectal Neoplasms; Urologic Neoplasms; Breast Neoplasms; Solid tumours; Digestive System Neoplasms; Small Cell Lung Carcinoma; Neoplasms; Carcinoma, Transitional Cell; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms, Fibroepithelial Details
Nimotuzumab biosimilar (IBC Generium) Phase 3 Clinical International Biotechnology Center Generium Llc Head and Neck Neoplasms Details
Depatuxizumab mafodotin ABT-414; ABT-414/806 Phase 3 Clinical Abbvie Inc Glioblastoma; Gliosarcoma; Carcinoma, Squamous Cell; Glioma Details
EG-007 EG-007 Phase 3 Clinical Endometrial Neoplasms Details
Larotinib Mesylate Z-650 Phase 3 Clinical Guangdong Dongyangguang Pharmaceutical Co Ltd Solid tumours; Esophageal Neoplasms; Pancreatic Neoplasms; Esophageal Squamous Cell Carcinoma Details
Ametumumab SY-101 Phase 2 Clinical Institute of Bioengineering Academy of Military Medical Sciences Chinese People's Liberation Army, Shanghai Serum Bio-Technology Co Ltd Solid tumours; Colorectal Neoplasms Details
BB-401 BB-401 Phase 2 Clinical Benitec Biopharma Ltd Squamous Cell Carcinoma of Head and Neck Details
Sutetinib Maleate Phase 2 Clinical Jiangsu Maidu Pharmaceutical R & D Co Ltd, Jiangsu Suzhong Pharma Group Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Petosemtamab MCLA-158 Phase 2 Clinical Merus Nv Solid tumours; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms; Neoplasm Metastasis Details
GC-1118A GC-1118; GC-1118A Phase 2 Clinical GC Biopharma Corp Solid tumours; Stomach Neoplasms; Colorectal Neoplasms; Neoplasm Metastasis Details
Durvalumab/Gefitinib Phase 2 Clinical Medimmune Carcinoma, Non-Small-Cell Lung Details
Pamvatamig MCLA-129 Phase 2 Clinical Merus Nv Solid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Esophageal Squamous Cell Carcinoma; Carcinoma, Non-Small-Cell Lung Details
JNJ-26483327 JNJ-26483327; MTKi-327; BGB-102 Phase 2 Clinical Johnson & Johnson Solid tumours; Neoplasms; Macular Degeneration Details
HER-1 vaccine (Center of Molecular Immunology) HER1-ECD; HER1-VSSP; HER-1-ECD-VSSP Phase 2 Clinical Center Of Molecular Immunology Neoplasms Details
AFM-24 AFM-24 Phase 2 Clinical Affimed Solid tumours Details
C225-ILS-DOX C225-ILs-dox Phase 2 Clinical Universitaetsspitals Basel Breast Neoplasms Details
Nazartinib EGF-816; EGFRmut-TKI EGF816 Phase 2 Clinical Novartis Pharma Ag Bronchial Neoplasms; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
Sapitinib AZD-8931 Phase 2 Clinical Astrazeneca Plc Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Tesevatinib XL-647; KD-020; KD-019; EXEL-7647 Phase 2 Clinical Exelixis Inc Glioblastoma; Neoplasms; Brain Neoplasms; Breast Neoplasms; Polycystic Kidney, Autosomal Dominant; Brain metastases; Polycystic Kidney, Autosomal Recessive; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
Futuximab/Modotuximab Sym-004; S95026; S-95026; 992-and-1024 Phase 2 Clinical Symphogen A/S Solid tumours; Carcinoma; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Glioma Details
DBPR-112 ABT-101; DBPR-112 Phase 2 Clinical National Health Research Institutes Solid tumours; Head and Neck Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Panitumumab-IRDye800CW (Stanford University) Phase 2 Clinical Stanford University Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck; Brain Neoplasms Details
AMX-3009 Maleate AMX-3009; AMX3009马来酸 Phase 2 Clinical Anrun Medicine Technology (Suzhou) Co Ltd Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Pancreatic Neoplasms; Breast Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
Allitinib Tosylate AST-6; ALS-1306; AST-1306 Phase 2 Clinical Shanghai Allist Pharmaceutical Technology Co Ltd Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Demupitamab SCT-200 Phase 2 Clinical SinoCelltech Ltd Ovarian Neoplasms; Biliary Tract Neoplasms; Solid tumours; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Carcinoma; Carcinoma, Renal Cell; Triple Negative Breast Neoplasms; Neoplasms; Pancreatic Neoplasms; Colorectal Neoplasms; Gallbladder Neoplasms; Esophageal Squamous Cell Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung Details
Cetuximab-IRDye800CW (University Medical Center Groningen) Phase 2 Clinical Umcg The University Medical Center Groningen Rectal Neoplasms; Small Cell Lung Carcinoma; Penile Neoplasms; Lung Neoplasms Details
Selatinib Ditosilate QLNC-120 Phase 2 Clinical Qilu Antibiotics (Linyi) Pharmaceutical Co Ltd, Qilu Pharmaceutical Co Ltd Breast Neoplasms Details
Pimurutamab HLX-07 Phase 2 Clinical Shanghai Henlius Biotech Inc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Stomach Neoplasms; Esophageal Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Adenosquamous; Carcinoma, Basosquamous; Nasopharyngeal Carcinoma; Colorectal Neoplasms; Lung Neoplasms; Esophageal Squamous Cell Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung Details
NRC-2694 NRC-2694; NRC-2694A; NRC-2694-A Phase 2 Clinical Natco Pharma Carcinoma; Squamous Cell Carcinoma of Head and Neck Details
Bafisontamab FIT-013a; EMB-01 Phase 2 Clinical Shanghai Epimab Biotherapeutics, Inc Biliary Tract Neoplasms; Liver Neoplasms; Carcinoid Tumor; Stomach Neoplasms; Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
Recombinant anti-EGFR chimeric monoclonal antibody (Shanghai CP Guojian) CPGJ-602; 602; CPGJ602; CPGJ 602 Phase 2 Clinical Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd Colorectal Neoplasms Details
GB-263 GB-263; GB-263T Phase 2 Clinical Genor Biopharma Co Ltd Solid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
ORIC-114 ORIC-114; VRN-07 Phase 2 Clinical Voronoi Inc Solid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
WJ-13404 WJ-13404; JS-113; WJ-004 Phase 2 Clinical Wigen Biomedicine technology (Shanghai) Co Ltd Carcinoma, Non-Small-Cell Lung Details
BDTX-1535 BDTX-1535 Phase 2 Clinical Black Diamond Therapeutics Inc Glioblastoma; Glioma; Carcinoma, Non-Small-Cell Lung Details
Neratinib (Fukang (Shanghai) Health Technology) CVL009; CVL-009 Phase 2 Clinical Solid tumours; Uterine Neoplasms; Carcinoma, Non-Small-Cell Lung Details
IBI-3001 IBI-3001; IBI3001 Phase 2 Clinical Innovent Biologics(Suzhou) Co Ltd Solid tumours Details
TRX-221 TRX-221 Phase 2 Clinical Therapex Corp Carcinoma, Non-Small-Cell Lung Details
E-EDV-D682 PNU-15982; E-EDV-D682; EGFR-EDV-PNU-15982 Phase 2 Clinical Engeneic Ltd Pancreatic Neoplasms Details
IBI334 IBI334; IBI-334 Phase 2 Clinical Innovent Biologics(Suzhou) Co Ltd Solid tumours; Neoplasms Details
DWP-708 DWP-708 Phase 2 Clinical Daewoong Pharmaceutical Co Ltd Acneiform Eruptions Details
BBT-207 BBT-207 Phase 2 Clinical Bridge Biotherapeutics Inc Carcinoma, Non-Small-Cell Lung Details
H-002 H-002 Phase 2 Clinical Nanjing Hongyun Biological Technology Co Ltd Neoplasms; Carcinoma, Non-Small-Cell Lung Details
DAJH-1050766 DAJH1050766; DAJH-1050766 Phase 2 Clinical Carcinoma, Non-Small-Cell Lung Details
Anti-CTLA-4/PD-1 expressing EGFR-CAR-T Phase 2 Clinical Shanghai Cell Therapy Research Institute Solid tumours Details
IAE-0972 IAE-0972 Phase 2 Clinical SunHo (China) BioPharmaceutical Co Ltd Solid tumours; Carcinoma, Hepatocellular Details
Anti-EGFR CAR-T cell therapy (Beijing Pregene) Phase 2 Clinical Shenzhen Prekin Biopharmaceutical Co Ltd Colorectal Neoplasms Details
BAY-2927088 BAY-2927088; BAY2927088 Phase 2 Clinical Bayer AG, Broad Institute, Harvard University Carcinoma, Non-Small-Cell Lung Details
HS-10375 HS-10375 Phase 2 Clinical Jiangsu Hansoh Pharmaceutical Group Co Ltd Carcinoma, Non-Small-Cell Lung Details
SMET-12 SMET-12 Phase 2 Clinical Zhejiang Shimai Pharmaceutical Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
EO-1001 NT-113; APL-122 Phase 2 Clinical Edison Pharmaceuticals Inc Neoplasms Details
TAK-186 EGFR x CD3 COBRA; MVC-101; TAK-186 Phase 2 Clinical Takeda Pharmaceutical Co Ltd Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
AP-L1898 JS111; WJ-002; AP-L1898 Phase 2 Clinical Wigen Biomedicine technology (Shanghai) Co Ltd Small Cell Lung Carcinoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
BPI-361175 BPI-361175 Phase 2 Clinical Betta Pharmaceuticals Co Ltd Carcinoma, Non-Small-Cell Lung Details
CKD-702 Phase 2 Clinical Chong Kun Dang Pharmaceutical Corp Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung Details
REGN-7075 REGN-7075 Phase 2 Clinical Solid tumours Details
JRF-103 JRF103; JRF-103 Phase 2 Clinical Shenzhen Jinrui Foundation Biotechnology Co Ltd Solid tumours Details
Anti-EGFR-IL-dox (Swiss Group for Clinical Cancer Research) Phase 2 Clinical Schweizerische Arbeitsgemeinschaft Für Klinische Krebsforschung Breast Neoplasms Details
FCN-411 FCN-411 Phase 2 Clinical Shanghai Fosun Pharmaceutical (Group) Co Ltd Small Cell Lung Carcinoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Epertinib S-222611 Phase 2 Clinical Shionogi & Co Ltd Neoplasms Details
Pirotinib Hydrochloride KBP-5209 Phase 2 Clinical Shandong Xuanzhu Pharmaceutical Technology Co Ltd Solid tumours; Breast Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Humanized anti-EGFR monoclonal antibody (Hualan Biological Engineering/Henan shengming biotechnology) Phase 2 Clinical Henan Shengming Biotechnology Research Institute Co Ltd, Hualan Genetic Engineering Co Ltd Colorectal Neoplasms Details
Anti-CD3/anti-EGFR -activated T cells (Barbara Ann Karmanos Cancer Institute) Phase 2 Clinical Barbara Ann Karmanos Cancer Institute, University Of Virginia Glioblastoma; Pancreatic Neoplasms Details
Cetuximab biosimilar (Guilin Sanjin) CDP-1; BC-001 Phase 1 Clinical Dragonboat Biopharmaceutical, Guilin Sanjin Pharmaceutical Co Ltd Solid tumours; Neoplasms; Colorectal Neoplasms Details
TQB3804 TQB-3804 Phase 1 Clinical Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Neoplasms; Carcinoma, Non-Small-Cell Lung Details
D2C7-based immunotoxins (Duke University) D2C7-IT; scds-D2C7 -PE38KDEL; D2C7-(scdsFv)-PE38 KDEL Phase 1 Clinical Istari Oncology Inc, Duke University Glioma Details
Anti-EGFR CAR T-cell therapy (Seattle Children's Hospital) EGFR-806 Phase 1 Clinical Seattle Children'S Hospital Sarcoma, Synovial; Neoplasms, Germ Cell and Embryonal; Diffuse Intrinsic Pontine Glioma; Retinoblastoma; Neuroblastoma; Sarcoma; Neurofibrosarcoma; Sarcoma, Ewing; Osteosarcoma; Sarcoma, Clear Cell; Rhabdomyosarcoma; Central Nervous System Neoplasms; Wilms Tumor; Carcinoma; Rhabdoid Tumor; Hepatoblastoma; Desmoplastic Small Round Cell Tumor; Diffuse midline glioma; Solid tumours Details
BPI-15086 BPI-15086; BPI-15000 Phase 1 Clinical Betta Pharmaceuticals Co Ltd Carcinoma, Non-Small-Cell Lung Details
Recombinant anti-human EGFR antibody/IL-10 bispecific Fc fusion protein(Dingfu Biotarget) CmAb-(IL10)2; DF203; DF-203 Phase 1 Clinical Dingfu Biotarget Co Ltd Solid tumours Details
MP-0274 DARPin-41; SPA-28; CME-114; CME-115; CME-118; CME-119; MP-0274 Phase 1 Clinical Molecular Partners Ag Neoplasms Details
SYN-004 (Synermore Biologics) LR-004; SYN-004 Phase 1 Clinical Lonn Ryonn Pharma Ltd, Synermore Biologics (Suzhou) Co Ltd Solid tumours; Carcinoma; Lymphoma, Large B-Cell, Diffuse; Colorectal Neoplasms Details
KY-1701 KY-1701 Phase 1 Clinical Jiangsu Kanion Pharmaceutical Co Ltd Breast Neoplasms Details
Simotinib Hydrochloride AL-6802; SIM-6802 Phase 1 Clinical Jiangsu Simcere Pharmaceutical Co Ltd, Advenchen Laboratories Llc Carcinoma, Non-Small-Cell Lung Details
Double-deleted Vaccinia Virus Plus CD/ SMR JX-929; vvDD-CDSR Phase 1 Clinical Sillajen Inc Liver Neoplasms; Squamous Cell Carcinoma of Head and Neck; Pancreatic Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Melanoma Details
WSD-0922 WSD-0922; WSD0922 Phase 1 Clinical Wayshine Biopharm International Ltd Glioblastoma; Neoplasms; Astrocytoma; Carcinoma, Non-Small-Cell Lung Details
TQ-B3395 TQ-B3395; CT-1495; TQ-B-3395 Phase 1 Clinical Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd, Beijing Centaurus Biopharma Co Ltd Neoplasms; Breast Neoplasms Details
Antibody-drug nanocell conjugates (EnGeneIC) EGFR-EDV-RRM1; EGFR-EDV-PLK; EGFR-EDV-Dox Phase 1 Clinical Engeneic Ltd Glioblastoma Details
Cetuximab biosimilar (Shanghai Henlius Biotech) HLX-05; JZB-29; JZB-28 Phase 1 Clinical Shanghai Henlius Biotech Inc Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms Details
Recombinant chimeric anti-EGFR monoclonal antibody (Zhejiang Xinwei Shengke Biotechnology) Phase 1 Clinical Zhejiang Xinweishengke Biotechnology Co Ltd Esophageal Neoplasms Details
Anti-EGFR-bispecific antibody armed activated T-cell therapy (Memorial Sloan Kettering Cancer Center) Phase 1 Clinical Memorial Sloan Kettering Cancer Center Pancreatic Neoplasms Details
[89Zr]Panitumumab Phase 1 Clinical Vanderbilt-Ingram Cancer Center, University Of Alabama At Birmingham, Stanford University Squamous Cell Carcinoma of Head and Neck; Colonic Neoplasms; Pancreatic Neoplasms Details
Recombinant chimeric anti-EGFR monoclonal antibody (Qilu Pharmaceutical) QL-1105 Phase 1 Clinical Qilu Pharmaceutical Co Ltd Solid tumours Details
EGFRvIII-CAR Phase 1 Clinical Duke University Medical Center Glioblastoma Details
14C-labeled poziotinib Phase 1 Clinical Spectrum Pharmaceuticals Solid tumours Details
BB-101 (Blue Blood Biotech/National Cheng Kung University) BB-101 Phase 1 Clinical National Cheng Kung University, Blue Blood Biotech Corp Diabetic Foot Details
Puvitinib Phase 1 Clinical Suzhou Teligene Ltd Solid tumours Details
Betatinib TL-512 Phase 1 Clinical Aspedia Llc, Suzhou Teligene Ltd Carcinoma, Non-Small-Cell Lung Details
KSP-QRH-E3-IRDye800 Phase 1 Clinical University Of Michigan Cholangiocarcinoma Details
Hemay-020 Hemay-020 Phase 1 Clinical Tianjin Hemay Pharmaceutical Co Ltd, Hainan General Sanyang Pharmaceutical Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
SGT-210 SGT-210 Phase 1 Clinical Sol Gel Technologies Pte Ltd Keratosis Details
Epitinib Succinate HMPL-813 Phase 1 Clinical Hutchison Medipharma Ltd Solid tumours; Neoplasms; Glioblastoma; Carcinoma, Non-Small-Cell Lung Details
ZN-e4 ZN-e4; KP-673 Phase 1 Clinical Zentalis Pharmaceuticals LLC, Zeno Pharma Carcinoma, Non-Small-Cell Lung Details
LY-01010 LY-01010 Phase 1 Clinical Luye Pharma Group Ltd Breast Neoplasms Details
PB-357 PB-357 Phase 1 Clinical Pfizer Inc Neoplasms Details
ZSP-0391 ZSP-0391 Phase 1 Clinical Wuxi Apptec Co Ltd, Guangdong Zhongsheng Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
Neptinib Di-P-methylbenzenesulfonate Phase 1 Clinical Shenzhen Neptunus Pharmaceutical Research Institute Co Ltd Stomach Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
QRH-882260 QRH-882260 Phase 1 Clinical University Of Michigan Cholangiocarcinoma Details
Serclutamab talirine ABBV-321 Phase 1 Clinical Abbvie Inc Neoplasms Details
Recombinant anti-EGFR chimeric antibody (Harbin Pharmaceutical) Phase 1 Clinical Harbin Pharmaceutical Group Holding Co Ltd Colorectal Neoplasms Details
Diakine-DK2 10 (EGFR) DK210; DK-2-10 Phase 1 Clinical Deka Biosciences Inc Kidney Neoplasms; Solid tumours; Head and Neck Neoplasms; Carcinoma, Renal Cell; Neoplasms; Pancreatic Neoplasms; Skin Neoplasms; Colorectal Neoplasms; Genital Neoplasms, Female; Carcinoma, Non-Small-Cell Lung Details
HLX-42 HLX-42; HLX42 Phase 1 Clinical Hanlin Biotechnology Co Ltd Solid tumours; Neoplasms Details
CMAB-017 CMAB-017 Phase 1 Clinical Taizhou Mabtech Pharmaceutical Co Ltd Solid tumours Details
JY-016 JY-016 Phase 1 Clinical Beijing Jingyitaixiang Technology Development Co Ltd, Beijing Eastern Biotech Co Ltd Solid tumours; Colorectal Neoplasms; Lung Neoplasms Details
PF-08046052 SGN-EGFRd2; LAVA-1223 Phase 1 Clinical Vu University Medical Center, Lava Therapeutics NV Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
CM-93 CM-93 Phase 1 Clinical Shanghai Crimson Pharmaceutical Co Ltd Glioblastoma Details
BLU-701 BLU-701; BLU 701 Phase 1 Clinical Blueprint Medicines Corp Carcinoma, Bronchogenic; Carcinoma; Thoracic Neoplasms; Bronchial Neoplasms; Neoplasms; Respiratory Tract Diseases; Lung Diseases; Respiratory Tract Neoplasms; Neoplasms, Nerve Tissue; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
CX-904 CX-904 Phase 1 Clinical Amgen Inc, Cytomx Therapeutics Inc Solid tumours; Neoplasms Details
Cetuximab biosimilar (Humanwell Healthcare) Phase 1 Clinical Humanwell Healthcare (Group) Co Ltd Colorectal Neoplasms Details
Sirotinib Maleate XZP-5491 Phase 1 Clinical Shandong Xuanzhu Pharmaceutical Technology Co Ltd Stomach Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung Details
Tomuzotuximab GT-MAB-5.2-GEX Phase 1 Clinical Glycotope Gmbh Solid tumours; Squamous Cell Carcinoma of Head and Neck Details
YL-221 YL221; YL-221 Phase 1 Clinical MediLink Therapeutics Co Ltd Solid tumours Details
[14C]-PLB1004 [14C]-PLB1004 Phase 1 Clinical Beijing Avistone Pharmaceuticals Biotechnology Co Ltd Carcinoma, Non-Small-Cell Lung Details
FPI-2107 [111In]-FPI-2107 Phase 1 Clinical Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
FPI-2053 FPI-2053 Phase 1 Clinical Astrazeneca Plc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
CPO-301 CPO301; CPO-301 Phase 1 Clinical CSPC Pharmaceutical Group Ltd Solid tumours; Neoplasms; Lung Neoplasms Details
FPI-2068 [225Ac]-FPI-2068; FPI-2068 Phase 1 Clinical Astrazeneca Plc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
HS-20117 HS-20117; PM1080; PM-1080 Phase 1 Clinical Biotheus Inc Solid tumours; Carcinoma, Non-Small-Cell Lung Details
SYS-6010 SYS6010; SYS-6010 Phase 1 Clinical Jushi Biopharmaceutical Co Ltd Solid tumours Details
SNC-109 SNC109; SNC-109 Phase 1 Clinical Shanghai Simnova Biotechnology Co Ltd Glioblastoma Details
HSK-40118 HSK40118; HSK-40118 Phase 1 Clinical Haisco Pharmaceutical Group Co Ltd Carcinoma, Non-Small-Cell Lung Details
AZD9592 AZD-9592; AZD9592 Phase 1 Clinical Astrazeneca Plc Solid tumours; Head and Neck Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
JANX-008 EGFR-TRACTr; JANX008; JANX-008 Phase 1 Clinical Janux Therapeutics Inc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
TAVO-412 TAVO-412 Phase 1 Clinical Tavotek Biotherapeutics (Hong Kong) Ltd, Tuochuang Biotechnology (Jiangsu) Co Ltd Solid tumours; Neoplasms Details
NX-019 NX-019 Phase 1 Clinical Nalo Therapeutics Inc Neoplasms Details
QLH-11811 QLH-11811; QLH11811 Phase 1 Clinical Qilu Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
Losatuxizumab vedotin ABBV-221; ABBV221 Phase 1 Clinical Abbvie Inc Neoplasms Details
EGFR/B7H3 CAR-T EGFR/B7H3 CAR-T Phase 1 Clinical Second Affiliated Hospital Of Guangzhou Medical University Triple Negative Breast Neoplasms; Lung Neoplasms Details
BB-1705 BB-1705 Phase 1 Clinical Bliss Biopharmaceutical (Hangzhou) Co Ltd Solid tumours; Neoplasms; Neoplasm Metastasis Details
CART-EGFR-IL13Ra2 CART-EGFR-IL13Ra2; CAR-T-EGFR-IL-13-Ra-2 Phase 1 Clinical University Of Pennsylvania Glioblastoma Details
EGFR IL12 CART Phase 1 Clinical Shenzhen Prekin Biopharmaceutical Co Ltd Colorectal Neoplasms Details
ERAS-801 ERAS-801 Phase 1 Clinical Regents Of The University Of California Glioblastoma Details
NIP-142 NIP-142 Phase 1 Clinical National Institutes Of Pharmaceutical Research And Development Co Ltd Carcinoma, Non-Small-Cell Lung Details
TAS-2940 TAS-2940 Phase 1 Clinical Taiho Oncology Inc Solid tumours; Glioblastoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
[111In] Panitumumab Phase 1 Clinical Stanford University Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck Details
BC-3448 BC3448; BC-3448 Phase 1 Clinical Solid tumours Details
ABBV-637 ABBV-637 Phase 1 Clinical Abbvie Inc Solid tumours; Carcinoma, Non-Small-Cell Lung Details
M-1231 M-1231 Phase 1 Clinical Emd Serono Research & Development Institute Inc, Merck Serono Solid tumours; Esophageal Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
HLX-35 HLX-35 Phase 1 Clinical Shanghai Henlius Biologics Co Ltd Solid tumours; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung Details
WTS-004 WTS-004 Phase 1 Clinical Hangzhou Wutong Tree Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
ES-072 ES-072 Phase 1 Clinical Zhejiang Bosheng Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
ZZ-06 ZZ-06 Phase 1 Clinical Changchun Intellicrown Pharmaceutical Co Ltd Solid tumours Details
ABY-029 ABY-029 Phase 1 Clinical Dartmouth College, Affibody Ab, Li-Cor Bioscience Head and Neck Neoplasms; Sarcoma; Glioma Details
Lifirafenib BeiGene-283; BGB-283 Phase 1 Clinical Beigene Ltd Solid tumours Details
Cetuximab biosimilar (Enzene Biosciences) Clinical Enzene Biosciences Ltd Carcinoma, Squamous Cell Details
VRN-11 VRN11 Clinical Voronoi Inc Carcinoma, Non-Small-Cell Lung Details

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